CAS 2466-76-4|1-acetylimidazole

Introduction：Basic information about CAS 2466-76-4|1-acetylimidazole, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles31
7. Synonyms

Common Name	1-acetylimidazole
CAS Number	2466-76-4	Molecular Weight	110.114
Density	1.1±0.1 g/cm3	Boiling Point	222.0±23.0 °C at 760 mmHg
Molecular Formula	C₅H₆N₂O	Melting Point	99-105 °C(lit.)
MSDS	ChineseUSA	Flash Point	88.0±22.6 °C

Names

Name	N-acetylimidazole
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	222.0±23.0 °C at 760 mmHg
Melting Point	99-105 °C(lit.)
Molecular Formula	C₅H₆N₂O
Molecular Weight	110.114
Flash Point	88.0±22.6 °C
Exact Mass	110.048012
PSA	34.89000
LogP	-0.34
Vapour Pressure	0.1±0.4 mmHg at 25°C
Index of Refraction	1.552
InChIKey	VIHYIVKEECZGOU-UHFFFAOYSA-N
SMILES	CC(=O)n1ccnc1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI3400000

CHEMICAL NAME :: Imidazole, 1-acetyl-

CAS REGISTRY NUMBER :: 2466-76-4

BEILSTEIN REFERENCE NO. :: 0108425

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C5-H6-N2-O

MOLECULAR WEIGHT :: 110.13

WISWESSER LINE NOTATION :: T5N CNJ AV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Immunological Including Allergic - decreased immune response

REFERENCE :: StoGD# Personal Communication from G.D. Stoner, Dept. of Community Medicine, School of Medicine, Univ. of California, La Jolla, CA 92037, May 25, 1975 Volume(issue)/page/year: 27MAY1975 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg/I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :: JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 54,495,1975

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn
Risk Phrases	R36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	NI3400000
HS Code	2933290090

Customs

HS Code	2933290090
Summary	2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles31

Involvement of conserved histidine, lysine and tyrosine residues in the mechanism of DNA cleavage by the caspase-3 activated DNase CAD.

Nucleic Acids Res. 30(6) , 1325-32, (2002)

The caspase-activated DNase (CAD) is involved in DNA degradation during apoptosis. Chemical modification of murine CAD with the lysine-specific reagent 2,4,6-trinitrobenzenesulphonic acid and the tyro...

Changes in the level and activation state of the plasma membrane H(+)-ATPase during aging of red beet slices.

Plant Physiol. 114(3) , 857-62, (1997)

The effect of aging on the plasma membrane (PM) H(+)-ATPase of red beet (Beta vulgaris L.) parenchyma discs was analyzed in PM purified by aqueous two-phase partitioning. Aging increased both the acti...

Chemical modification of active site residues in gamma-glutamyl transpeptidase. Aspartate 422 and cysteine 453.

J. Biol. Chem. 270(21) , 12476-80, (1995)

gamma-Glutamyl transpeptidase, an enzyme of central significance in glutathione metabolism, is inactivated by iodoacetamide, which esterifies an active site carboxyl group identified here as that of A...

Synonyms

MFCD00005287

N-Acetylimidazole

1-Acetyl-1H-imidazole

Ethanone, 1-(1H-imidazol-1-yl)-

EINECS 219-577-7

1-(1H-Imidazol-1-yl)ethanone

Acetylimidazole

1-acetylimidazole

IMIDAZOLE,1-ACETYL

1H-Imidazole,1-acetyl

1-imidazol-1-ylethanone

Recommended......