CAS 112-05-0|Nonanoic acid
Introduction：Basic information about CAS 112-05-0|Nonanoic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Nonanoic acid | ||
|---|---|---|---|
| CAS Number | 112-05-0 | Molecular Weight | 158.23800 |
| Density | 0.906 g/mL at 25 °C(lit.) | Boiling Point | 268-269 °C(lit.) |
| Molecular Formula | C9H18O2 | Melting Point | 9 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 212 °F |
| Symbol | GHS05 | Signal Word | Danger |
Names
| Name | pelargonic acid |
|---|---|
| Synonym | More Synonyms |
Nonanoic acid BiologicalActivity
| Description | Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2[1]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
| In Vitro | Nonanoic acid upregulates endogenous host defense peptides to enhance intestinal epithelial immunological barrier function via histone deacetylase inhibition[1]. |
| References | [1]. Wang J, et al. Caprylic acid and nonanoic acid upregulate endogenous host defense peptides to enhance intestinal epithelial immunological barrier function via histone deacetylase inhibition.Int Immunopharmacol. 2018 Dec;65:303-311. |
Chemical & Physical Properties
| Density | 0.906 g/mL at 25 °C(lit.) |
|---|---|
| Boiling Point | 268-269 °C(lit.) |
| Melting Point | 9 °C(lit.) |
| Molecular Formula | C9H18O2 |
| Molecular Weight | 158.23800 |
| Flash Point | 212 °F |
| Exact Mass | 158.13100 |
| PSA | 37.30000 |
| LogP | 2.82160 |
| Vapour density | 5.5 (vs air) |
| Vapour Pressure | <0.1 mm Hg ( 20 °C) |
| Index of Refraction | n20/D 1.432(lit.) |
| InChIKey | FBUKVWPVBMHYJY-UHFFFAOYSA-N |
| SMILES | CCCCCCCCC(=O)O |
| Storage condition | 2-8°C |
| Water Solubility | NEGLIGIBLE |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,839,1978
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- EMERY* Emery Industries, Inc., Data Sheets. (4900 Este Ave., Cincinnati, OH 45232) Volume(issue)/page/year: S3B,-,1964
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,839,1978 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 224 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 18,141,1961 *** REVIEWS *** TOXICOLOGY REVIEW AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 21,100,1960 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83209 No. of Facilities: 960 (estimated) No. of Industries: 9 No. of Occupations: 16 No. of Employees: 7870 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83209 No. of Facilities: 2266 (estimated) No. of Industries: 49 No. of Occupations: 46 No. of Employees: 76346 (estimated) No. of Female Employees: 6777 (estimated)
Safety Information
| Symbol | GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314 |
| Precautionary Statements | P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | C:Corrosive; |
| Risk Phrases | R34 |
| Safety Phrases | S26-S28-S36/37/39-S45-S28A |
| RIDADR | UN 3265 8/PG 3 |
| WGK Germany | 1 |
| RTECS | RA6650000 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 2915900090 |
Customs
| HS Code | 2915900090 |
|---|---|
| Summary | 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0% |
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Synonyms
| nonanic acid |
| n-Nonanoic acid |
| NONANOIC-D4 ACID |
| NONANOIC ACID FOR SYNTHESIS |
| Nonanoic acid |
| nonyloic acid |
| Nona-N-methyl-4,4',4''-methantriyl-tri-anilinium,Tris-jodid |
| NONANOIC ACID/PELARGONIC ACID |
| NONANOICACID(PELARGONICACID) |
| nona-N-methyl-4,4',4''-methanetriyl-tri-anilinium,tris iodide |
| Nonanoic acid (Pelargonic acid) |
| noncarboxylic acid |
| N-NONYLIC ACID |
| NONANOIC ACID (PELARGONIC) |
| Acid C9,Pelargonic acid |
| Pelargonic Acid |
| MFCD00004433 |
| Nonoic acid |
| EINECS 203-931-2 |
| NO0NOIC ACID |
