Introduction：Basic information about CAS 72895-88-6|Eltenac, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Eltenac |
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| CAS Number | 72895-88-6 | Molecular Weight | 302.18 |
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| Density | 1.539g/cm3 | Boiling Point | 419.4ºC at 760 mmHg |
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| Molecular Formula | C12H9Cl2NO2S | Melting Point | / |
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| MSDS | / | Flash Point | 207.4ºC |
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Names
| Name | 2-[4-(2,6-dichloroanilino)thiophen-3-yl]acetic acid |
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| Synonym | More Synonyms |
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Eltenac BiologicalActivity
| Description | Eltenac, a non-steroidal anti-inflammatory drug (NSAID), is a COX inhibitor. Eltenac shows IC50 of 0.03 μM for both COX-1 and COX-2 in isolated human whole blood[1]. |
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| Related Catalog | Research Areas >>Inflammation/ImmunologySignaling Pathways >>Immunology/Inflammation >>COX |
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| Target | COX-1:0.03 μM (IC50) COX-2:0.03 μM (IC50) |
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| In Vitro | Eltenac (10 mg/kg; p.o.; Female Sprague-Dawley rats weighing150-190; rat paw edema model) efficaciously reduces the increase in paw volume by 52%[1]. |
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| References | [1]. Klein T,, et al. Characterization of eltenac and novel COX-2 selective thiopheneacetic acid analogues in vitro and in vivo. Biochem Pharmacol. 2008;76(6):717-725. |
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Chemical & Physical Properties
| Density | 1.539g/cm3 |
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| Boiling Point | 419.4ºC at 760 mmHg |
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| Molecular Formula | C12H9Cl2NO2S |
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| Molecular Weight | 302.18 |
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| Flash Point | 207.4ºC |
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| Exact Mass | 300.97300 |
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| PSA | 77.57000 |
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| LogP | 4.49860 |
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| Index of Refraction | 1.688 |
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| InChIKey | AELILMBZWCGOSB-UHFFFAOYSA-N |
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| SMILES | O=C(O)Cc1cscc1Nc1c(Cl)cccc1Cl |
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Safety Information
| Hazard Codes | T+ |
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| HS Code | 2934999090 |
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Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 4-(2,6-dichloroanilino)-3-thiophenacetic acid |
| Telzenac (TN) |
| ELTENAC |
| Eltenaco |
| Eltenacum |
| 4-(2,6-dichloroanilino)-3-thiopheneacetic acid |
| [4-(2,6-dichlorophenylamino)-thiophen-3-yl] acetic acid |
| Eltenac (INN) |
| Telzenac |
| Eltenaco [Spanish] |
| Eltenacum [Latin] |
