Introduction：Basic information about CAS 74050-20-7|Hydrocortisone aceponate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Hydrocortisone aceponate |
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| CAS Number | 74050-20-7 | Molecular Weight | 460.56000 |
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| Density | 1.23g/cm3 | Boiling Point | 589.3ºC at 760 mmHg |
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| Molecular Formula | C26H36O7 | Melting Point | 144-146ºC |
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| MSDS | / | Flash Point | 192.4ºC |
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Names
| Name | Hydrocortisone |
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| Synonym | More Synonyms |
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Hydrocortisone aceponate BiologicalActivity
| Description | Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is a potent topical glucocorticoid. Hydrocortisone aceponate can be used for various dermatoses research[1]. |
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| Related Catalog | Research Areas >>Inflammation/ImmunologySignaling Pathways >>GPCR/G Protein >>Glucocorticoid Receptor |
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| References | [1]. Amiya Kumar Mukhopadhyay, et al. A study to evaluate the efficacy and safety of hydrocortisone aceponate 0.127% lipophilic cream in steroid responsive dermatoses in Indian patients. Indian J Dermatol Venereol Leprol. Sep-Oct 2010;76(5):591. |
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Chemical & Physical Properties
| Density | 1.23g/cm3 |
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| Boiling Point | 589.3ºC at 760 mmHg |
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| Melting Point | 144-146ºC |
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| Molecular Formula | C26H36O7 |
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| Molecular Weight | 460.56000 |
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| Flash Point | 192.4ºC |
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| Exact Mass | 460.24600 |
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| PSA | 106.97000 |
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| LogP | 3.31330 |
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| Index of Refraction | 1.552 |
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| InChIKey | MFBMYAOAMQLLPK-FZNHGJLXSA-N |
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| SMILES | CCC(=O)OC1(C(=O)COC(C)=O)CCC2C3CCC4=CC(=O)CCC4(C)C3C(O)CC21C |
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Synonyms
| hydrocortisone aceponate |
| [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate |
| propionic acid [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetoxyacetyl)-11-hydroxy-3-keto-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] ester |
| [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyethanoyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate |
| Hydrocortison-17-propionat-21-acetat |
