CAS 52867-74-0|Zoloperone

Introduction：Basic information about CAS 52867-74-0|Zoloperone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameZoloperone
CAS Number52867-74-0Molecular Weight397.44300
Density1.24g/cm3Boiling Point/
Molecular FormulaC22H24FN3O3Melting Point/
MSDS/Flash Point/

Names

Name4-(4-fluorophenyl)-5-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-3H-1,3-oxazol-2-one
SynonymMore Synonyms

Chemical & Physical Properties

Density1.24g/cm3
Molecular FormulaC22H24FN3O3
Molecular Weight397.44300
Exact Mass397.18000
PSA61.71000
LogP3.15020
Index of Refraction1.582
InChIKeyFCMGKQUKZIJJSH-UHFFFAOYSA-N
SMILESCOc1ccccc1N1CCN(CCc2oc(=O)[nH]c2-c2ccc(F)cc2)CC1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RQ5832380
CHEMICAL NAME :
2(3H)-Oxazolone, 4-(4-fluorophenyl)-5-(2-(4-(2-methoxyphenyl)-1-pipera zinyl)ethyl)-
CAS REGISTRY NUMBER :
52867-74-0
LAST UPDATED :
199612
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C22-H24-F-N3-O3
MOLECULAR WEIGHT :
397.49

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHMGBN Pharmacology: International Journal of Experimental and Clinical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1968- Volume(issue)/page/year: 15,485,1977
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHMGBN Pharmacology: International Journal of Experimental and Clinical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1968- Volume(issue)/page/year: 15,485,1977
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHMGBN Pharmacology: International Journal of Experimental and Clinical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1968- Volume(issue)/page/year: 15,485,1977
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 32,2241,1989
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHMGBN Pharmacology: International Journal of Experimental and Clinical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1968- Volume(issue)/page/year: 15,485,1977
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHMGBN Pharmacology: International Journal of Experimental and Clinical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1968- Volume(issue)/page/year: 15,485,1977
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHMGBN Pharmacology: International Journal of Experimental and Clinical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1968- Volume(issue)/page/year: 15,485,1977
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHMGBN Pharmacology: International Journal of Experimental and Clinical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1968- Volume(issue)/page/year: 15,485,1977

Synonyms

2(3H)-Oxazolone,4-(4-fluorophenyl)-5-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)
Zoloperonum [INN-Latin]
Zoloperone
4-(4-fluoro-phenyl)-5-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-3H-oxazol-2-one
4-(p-Fluorophenyl)-5-(2-(4-(o-methoxyphenyl)-1-piperazinyl)ethyl)-4-oxazolin-2-one
LR 511
Zoloperona [INN-Spanish]
4-(4-Fluorophenyl)-5-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-2(3H)-oxazolone
4-p-fluorophenyl-5-N-(N'-o-methoxy-phenyl)piperazinoethyl-4-oxazolin-2-one
2-oxazolol,4-(4-fluorophenyl)-5-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]
CAS 123482-22-4|5-CHLORO-2,2-DIMETHYL-N-(8-METHYL-8-AZABICYCLO[3.2.1]OCTAN-3-YL)-2,3-DIHYDROB
CAS 24477-37-0|N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methyl-1,2-oxazole-3-car
Recommended......
CAS 529-84-0|6,7-Dihydroxy-4-m CAS 5213-49-0|2,4-Dinitro-1H-i CAS 52190-35-9|2-(methylthio)c CAS 52606-01-6|2,6-DIMETHOXYIS CAS 5234-26-4|Acetanilide, 2-a CAS 52468-60-7|Flunarizine CAS 52099-27-1|1-(2-FURYLMETHY CAS 5291-77-0|1-Benzyl-3-pyrro CAS 5296-40-2|Oxirane,2-[(2,4, CAS 52598-02-4|5-Chloro-2,3-di CAS 522598-05-6|2-(2-CHLOROPHE CAS 52094-95-8|2-(3-CHLOROPHEN CAS 52803-62-0|2-[(4-CHLOROBEN CAS 52803-64-2|3-METHOXY-2-[(4 CAS 5220-83-7|3-Amino-6-chloro CAS 52210-86-3|1-(4-Piperidiny CAS 52600-50-7|5-Cyano-2,6-dih CAS 526-34-1|3-METHOXY-4,5-MET CAS 52839-45-9|3,4-diphenyliso CAS 529508-58-5|1-(3-Fluoroben
Disclaimer

This site is a non-commercial website, not accept any sponsorship and advertising. The content is collated from the Internet, does not represent the position of this site, for personal reference only, please distinguish by yourself! The belongs to the original author.

Copyright © 2025 All Rights Reserved.

TOP