CAS 24467-92-3|2-(6-METHOXY-3-OXO-2,3-DIHYDRO-1H-INDEN-1-YL)ACETIC ACID

Introduction：Basic information about CAS 24467-92-3|2-(6-METHOXY-3-OXO-2,3-DIHYDRO-1H-INDEN-1-YL)ACETIC ACID, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles1
7. Synonyms

Common Name	2-(6-METHOXY-3-OXO-2,3-DIHYDRO-1H-INDEN-1-YL)ACETIC ACID
CAS Number	24467-92-3	Molecular Weight	220.22100
Density	1.286g/cm3	Boiling Point	428.7ºC at 760mmHg
Molecular Formula	C₁₂H₁₂O₄	Melting Point	139-144ºC(lit.)
MSDS	ChineseUSA	Flash Point	170.6ºC

Names

Name	2-(6-methoxy-3-oxo-1,2-dihydroinden-1-yl)acetic acid
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.286g/cm3
Boiling Point	428.7ºC at 760mmHg
Melting Point	139-144ºC(lit.)
Molecular Formula	C₁₂H₁₂O₄
Molecular Weight	220.22100
Flash Point	170.6ºC
Exact Mass	220.07400
PSA	63.60000
LogP	1.83990
Vapour Pressure	4.11E-08mmHg at 25°C
Index of Refraction	1.569
InChIKey	QOTZOFGBBCMWEP-UHFFFAOYSA-N
SMILES	COc1ccc2c(c1)C(CC(=O)O)CC2=O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NK8225760

CHEMICAL NAME :: 1H-Indene-1-acetic acid, 2,3-dihydro-6-methoxy-3-oxo-

CAS REGISTRY NUMBER :: 24467-92-3

BEILSTEIN REFERENCE NO. :: 2118149

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C12-H12-O4

MOLECULAR WEIGHT :: 220.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IJPPAZ Indian Journal of Physiology and Pharmacology. (All India Institute of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029, India) V.1- 1957- Volume(issue)/page/year: 24,310,1980

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	NK8225760
HS Code	2918990090

Customs

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles1

Selective inhibition of the chymotrypsin-like activity of the 20S proteasome by 5-methoxy-1-indanone dipeptide benzamides.

Bioorg. Med. Chem. Lett. 8(3) , 209-14, (1998)

Potent inhibitors of the 20S proteasome that contain a novel indanone head group coupled to di and tripeptides are described. These compounds are the first proteasome inhibitors have demonstrated high...

Synonyms

(6-Methoxy-3-oxo-indan-1-yl)-essigsaeure

1H-Indene-1-acetic acid,2,3-dihydro-6-methoxy-3-oxo

6-Methoxy-3-oxo-1-indanacetic acid

2-(6-methoxy-3-oxo-2,3-dihydro-1H-inden-1-yl)ethanoic acid

(6-methoxy-3-oxo-indan-1-yl)-acetic acid

MFCD00003787

6-Methoxy-3-oxo-2,3-dihydro-1H-indene-1-acetic acid

2-(6-methoxy-3-oxo-2,3-dihydro-1H-inden-1-yl)acetic acid

5-Methoxy-1-indanone-3-acetic acid

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