CAS 42856-71-3|2-Methyl-L-proline

Introduction:Basic information about CAS 42856-71-3|2-Methyl-L-proline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2-Methyl-L-proline
CAS Number42856-71-3Molecular Weight129.157
Density1.1±0.1 g/cm3Boiling Point241.9±33.0 °C at 760 mmHg
Molecular FormulaC6H11NO2Melting Point310 °C
MSDSChineseUSAFlash Point100.1±25.4 °C

Names

Name(S)-2-Methylpyrrolidine-2-carboxylic acid
SynonymMore Synonyms

2-Methyl-L-proline BiologicalActivity

Description(S)-2-Methylpyrrolidine-2-carboxylic acid is a proline derivative[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
In VitroAmino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point241.9±33.0 °C at 760 mmHg
Melting Point310 °C
Molecular FormulaC6H11NO2
Molecular Weight129.157
Flash Point100.1±25.4 °C
Exact Mass129.078979
PSA49.33000
LogP-0.03
Vapour Pressure0.0±1.0 mmHg at 25°C
Index of Refraction1.475
Storage condition-15°C

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety PhrasesS22-S24/25
RIDADRNONH for all modes of transport
WGK Germany3
HS Code2933990090

Customs

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles7

More Articles
Effects of ring contraction on the conformational preferences of α-substituted proline analogs.

Biopolymers 98(2) , 98-110, (2012)

The structural consequences derived from the incorporation of either a methyl or a phenyl group at the α carbon of proline were recently investigated by quantum mechanical calculations (J Org Chem 200...

Beta-turns induced in bradykinin by (S)-alpha-methylproline.

FEBS Lett. 297(3) , 216-20, (1992)

The ability of (S)-alpha-methylproline (alpha-MePro) to stabilise reverse-turn conformations in the peptide hormone bradykinin (BK = Arg1-Pro2-Pro3-Gly4-Phe5-Ser6-Pro7-Phe8-Arg9) has been investigated...

alpha-Methylproline-containing renin inhibitory peptides: in vivo evaluation in an anesthetized, ganglion-blocked, hog renin infused rat model.

J. Med. Chem. 30(3) , 536-41, (1987)

A structure-activity analysis of peptides containing backbone C alpha-methyl modification at the P4 site of the angiotensinogen sequence led to the discovery of potent renin inhibitors with apparent i...

Synonyms

MFCD01318647
α-Methyl-L-proline
L-Proline, 2-methyl-
2-Methyl-L-proline
(2S)-2-methylpyrrolidine-2-carboxylic acid,hydrochloride
(S)-2-Methyl proline
CAS 92-52-4|Biphenyl
CAS 636-79-3|3-Pyridinecarboxylicacid, hydrochloride (1:1)
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