CAS 76-42-6|oxycodone

Introduction：Basic information about CAS 76-42-6|oxycodone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Articles51
6. Synonyms

Common Name	oxycodone
CAS Number	76-42-6	Molecular Weight	315.364
Density	1.4±0.1 g/cm3	Boiling Point	501.6±50.0 °C at 760 mmHg
Molecular Formula	C₁₈H₂₁NO₄	Melting Point	218-220°
MSDS	/	Flash Point	257.1±30.1 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	oxycodone
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	501.6±50.0 °C at 760 mmHg
Melting Point	218-220°
Molecular Formula	C₁₈H₂₁NO₄
Molecular Weight	315.364
Flash Point	257.1±30.1 °C
Exact Mass	315.147064
PSA	59.00000
LogP	1.67
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.659
InChIKey	BRUQQQPBMZOVGD-XFKAJCMBSA-N
SMILES	COc1ccc2c3c1OC1C(=O)CCC4(O)C(C2)N(C)CCC314
Storage condition	2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QD2450000

CHEMICAL NAME :: Morphinan-6-one, 4,5-alpha-epoxy-14-hydroxy-3-methoxy-17-methyl-

CAS REGISTRY NUMBER :: 76-42-6

BEILSTEIN REFERENCE NO. :: 0043446

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C18-H21-N-O4

MOLECULAR WEIGHT :: 315.40

WISWESSER LINE NOTATION :: T B6566 B6/CO 4ABBC R BX FV HO PN GHT&&TTJ CQ JO1 P1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,261,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 426 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 28ZNAE "Public Health Reports, Supplement." (Washington, DC) Volume(issue)/page/year: 138,27,1938

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Hazard Codes	F,T
Risk Phrases	11-23/24/25-39/23/24/25
Safety Phrases	7-16-36/37-45
RIDADR	UN 1544
Packaging Group	II
Hazard Class	6.1(a)

Articles51

Inhibition of TRPM8 channels reduces pain in the cold pressor test in humans.

J. Pharmacol. Exp. Ther. 351(2) , 259-69, (2014)

The transient receptor potential (subfamily M, member 8; TRPM8) is a nonselective cation channel localized in primary sensory neurons, and is a candidate for cold thermosensing, mediation of cold pain...

Spontaneous resolution of quadrilateral space syndrome: a case report.

Am. J. Phys. Med. Rehabil. 94(1) , e1-5, (2015)

A case of quadrilateral space syndrome is presented, where a large near-circumferential glenoid labrum tear led to a paralabral cyst that dissected into the quadrilateral space and caused a compressiv...

Rational prescribing.

Minn. Med. 96(3) , 4, (2013)

Synonyms

Thecodine

Tekodin

Oxycodon

(5α)-14-hydroxy-17-methyl-3-(methyloxy)-4,5-epoxymorphinan-6-one

14-hydroxy-dihydrocodeinone

Oxycon

Oxikon

Eubine

oxanest

(1S,5R,13R,17S)-17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0.0.0]octadeca-7(18),8,10-trien-14-one

Eucodalum

Eukodal

oxycodone

Oxicon

(-)-14-Hydroxydihydrocodeinone

Dihydrone

percocet

(1S,5R,13R,17S)-17-Hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0.0.0]octadeca-7(18),8,10-trien-14-on

Tecodin

Thekodin

Percodan

Oxicone

Morphinan-6-one, 4,5α-epoxy-14-hydroxy-3-methoxy-17-methyl-

(1S,5R,13R,17S)-17-hydroxy-10-méthoxy-4-méthyl-12-oxa-4-azapentacyclo[9.6.1.0.0.0]octadéca-7(18),8,10-trién-14-one

Morphinan-6-one, 4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-, (5α)-

Morphinan-6-one,4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-, (5a)-

Eutagen

(5α)-14-Hydroxy-3-methoxy-17-methyl-4,5-epoxymorphinan-6-one

14-Hydroxydihydrocodeinone

Dihydrohydroxycodeinone

(5a)-4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one

endone

EINECS 200-960-2

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