CAS 146255-66-5|(RS)-3,5-DHPG
Introduction:Basic information about CAS 146255-66-5|(RS)-3,5-DHPG, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (RS)-3,5-DHPG | ||
|---|---|---|---|
| CAS Number | 146255-66-5 | Molecular Weight | 183.16100 |
| Density | 1.55g/cm3 | Boiling Point | 448.8ºC at 760mmHg |
| Molecular Formula | C8H9NO4 | Melting Point | / |
| MSDS | / | Flash Point | 225.2ºC |
Names
| Name | (S)-3,5-dihydroxyphenylglycine |
|---|---|
| Synonym | More Synonyms |
(RS)-3,5-DHPG BiologicalActivity
| Description | DHPG ((RS)-3,5-DHPG) is an amino acid, which acts as a selective and potent agonist of group I mGluR (mGluR 1 and mGluR 5), shows no effect on Group II or Group III mGluRs[1]. DHPG ((RS)-3,5-DHPG) is also an effective antagonist of mGluRs linked to phospholipase D[2]. |
|---|---|
| Related Catalog | Signaling Pathways >>GPCR/G Protein >>mGluR |
| Target | mGluR 1 mGluR 5 |
| References | [1]. Winder DG, et al. Metabotropic glutamate receptor (mGluR)-mediated potentiation of cyclic AMP responses does not require phosphoinositide hydrolysis: mediation by a group II-like mGluR. J Neurochem. 1995 Feb;64(2):592-9. [2]. Pellegrini-Giampietro DE, et al. Pharmacological characterization of metabotropic glutamate receptors coupled to phospholipase D in the rat hippocampus. Br J Pharmacol. 1996 Jun;118(4):1035-43. |
Chemical & Physical Properties
| Density | 1.55g/cm3 |
|---|---|
| Boiling Point | 448.8ºC at 760mmHg |
| Molecular Formula | C8H9NO4 |
| Molecular Weight | 183.16100 |
| Flash Point | 225.2ºC |
| Exact Mass | 183.05300 |
| PSA | 103.78000 |
| LogP | 0.88250 |
| InChIKey | HOOWCUZPEFNHDT-UHFFFAOYSA-N |
| SMILES | NC(C(=O)O)c1cc(O)cc(O)c1 |
Synonyms
| (RS)-3,5-DHPG |
| tert-Butylisopentanal |
| HEXANAL,3,5,5-TRIMETHYL |
| Isononylaldehyde |
| 3,5,5-Trimethylcapronaldehyde |
| 3,5,5,-trimethylhexanal |
| Hexanal,3,5,5-trimethl |
