CAS 14737-91-8|2-Methoxycinnamic acid

Introduction：Basic information about CAS 14737-91-8|2-Methoxycinnamic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles1
7. Synonyms

Common Name	2-Methoxycinnamic acid
CAS Number	14737-91-8	Molecular Weight	178.185
Density	1.2±0.1 g/cm3	Boiling Point	325.1±17.0 °C at 760 mmHg
Molecular Formula	C₁₀H₁₀O₃	Melting Point	94-96ºC(lit.)
MSDS	ChineseUSA	Flash Point	130.3±14.4 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	cis-O-Methyl-o-coumaric Acid
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	325.1±17.0 °C at 760 mmHg
Melting Point	94-96ºC(lit.)
Molecular Formula	C₁₀H₁₀O₃
Molecular Weight	178.185
Flash Point	130.3±14.4 °C
Exact Mass	178.062988
PSA	46.53000
LogP	2.42
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.591
InChIKey	FEGVSPGUHMGGBO-SREVYHEPSA-N
SMILES	COc1ccccc1C=CC(=O)O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GD9720000

CHEMICAL NAME :: Cinnamic acid, o-methoxy-, (Z)-

CAS REGISTRY NUMBER :: 14737-91-8

BEILSTEIN REFERENCE NO. :: 2209713

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C10-H10-O3

MOLECULAR WEIGHT :: 178.20

WISWESSER LINE NOTATION :: QV1U1R BO1 -C

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 119,443,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 119,443,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 119,443,1959

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	22-36/37/38
Safety Phrases	S26
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	GD9720000
HS Code	2918990090

Customs

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles1

Cinnamomum cassia essential oil inhibits α-MSH-induced melanin production and oxidative stress in murine B16 melanoma cells.

Int. J. Mol. Sci. 14(9) , 19186-201, (2013)

Essential oils extracted from aromatic plants exhibit important biological activities and have become increasingly important for the development of aromatherapy for complementary and alternative medic...

Synonyms

trans-ortho-methoxy-cinnamic acid

2-Propenoic acid, 3-(2-methoxyphenyl)-, (2Z)-

(2E)-3-(2-Methoxyphenyl)acrylic acid

MFCD00004375

2-Methoxycinnamic acid

(2Z)-3-(2-Methoxyphenyl)acrylic acid

cis-2-MethoxycinnaMic Acid

o-methoxy cinnamic acid

(Z)-3-(2-methoxyphenyl)prop-2-enoic acid

2-Propenoic acid, 3-(2-methoxyphenyl)-, (2E)-

cis-O-Methyl-o-cumaric Acid

EINECS 238-803-5

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