CAS 528-53-0|Delphinidin chloride
| Common Name | Delphinidin chloride | ||
|---|---|---|---|
| CAS Number | 528-53-0 | Molecular Weight | 338.697 |
| Density | 1.3946 (rough estimate) | Boiling Point | 454.94°C (rough estimate) |
| Molecular Formula | C15H11ClO7 | Melting Point | >350ºC |
| MSDS | ChineseUSA | Flash Point | / |
Names
| Name | delphinidin chloride |
|---|---|
| Synonym | More Synonyms |
Delphinidin chloride BiologicalActivity
| Description | Delphinidin chloride, an anthocyanidin, is isolated from berries and red wine. Delphinidin chloride shows endothelium-dependent vasorelaxation. Delphinidin chloride also can modulate JAK/STAT3 and MAPKinase signaling to induce apoptosis in HCT116 cells[1][2][3]. |
|---|---|
| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisSignaling Pathways >>Stem Cell/Wnt >>STATResearch Areas >>CancerResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>JAK/STAT Signaling >>JAKSignaling Pathways >>Epigenetics >>JAKSignaling Pathways >>Stem Cell/Wnt >>JAKSignaling Pathways >>JAK/STAT Signaling >>STAT |
| References | [1]. Nyman NA, et, al. Determination of anthocyanidins in berries and red wine by high-performance liquid chromatography. J Agric Food Chem. 2001 Sep;49(9):4183-7. [2]. Andriambeloson E, et, al. Natural dietary polyphenolic compounds cause endothelium-dependent vasorelaxation in rat thoracic aorta. J Nutr. 1998 Dec;128(12):2324-33. [3]. Zhang Z, et, al. Delphinidin modulates JAK/STAT3 and MAPKinase signaling to induce apoptosis in HCT116 cells. Environ Toxicol. 2021 May 6. |
Chemical & Physical Properties
| Density | 1.3946 (rough estimate) |
|---|---|
| Boiling Point | 454.94°C (rough estimate) |
| Melting Point | >350ºC |
| Molecular Formula | C15H11ClO7 |
| Molecular Weight | 338.697 |
| Exact Mass | 338.019318 |
| PSA | 134.52000 |
| Index of Refraction | 1.4429 (estimate) |
| InChIKey | FFNDMZIBVDSQFI-UHFFFAOYSA-N |
| SMILES | Oc1cc(O)c2cc(O)c(-c3cc(O)c(O)c(O)c3)[o+]c2c1.[Cl-] |
| Storage condition | −20°C |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >6 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHYREH Phytotherapy Research. (Heyden & Son Ltd., Spectrum House, Hillview Gardens, London, NW4 2JQ, UK) V.1- 1987- Volume(issue)/page/year: 6,99,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4229439
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >6 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHYREH Phytotherapy Research. (Heyden & Son Ltd., Spectrum House, Hillview Gardens, London, NW4 2JQ, UK) V.1- 1987- Volume(issue)/page/year: 6,99,1992
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | DK1310000 |
| HS Code | 2907299090 |
Customs
| HS Code | 2907299090 |
|---|---|
| Summary | 2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0% |
Articles32
More Articles| The metabolism of dietary polyphenols and the relevance to circulating levels of conjugated metabolites. Free Radic. Res. 36(11) , 1229-41, (2002) Berry extracts rich in anthocyanins have been linked to protective effects including the modulation of age-related neurological dysfunction and the improvement of the resistance of red blood cells aga... | |
| Transcriptome sequencing and metabolite analysis reveals the role of delphinidin metabolism in flower colour in grape hyacinth. J. Exp. Bot. 65(12) , 3157-64, (2014) Grape hyacinth (Muscari) is an important ornamental bulbous plant with an extraordinary blue colour. Muscari armeniacum, whose flowers can be naturally white, provides an opportunity to unravel the co... | |
| Functional characterization of an anthocyanidin reductase gene from the fibers of upland cotton (Gossypium hirsutum). Planta 241(5) , 1075-89, (2015) Metabolic profiling, gene cloning, enzymatic analysis, ectopic expression, and gene silencing experiments demonstrate that the anthocyanidin reductase (ANR) pathway is involved in the biosynthesis of ... |
Synonyms
| T66 BOJ CR CQ DQ DQ& GQ IQ &&Chloride |
| 2-(3,4,5-trihydroxyphenyl)chromenylium-3,5,7-triol,chloride |
| 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)chromenium chloride |
| Delphinidin chloride |
| 3,3',4',5,5',7-hexahydroxy-2-phenylbenzopyrylium chloride |
| 1-Benzopyrylium, 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-, chloride (1:1) |
