Introduction：Basic information about CAS 522-87-2|Yohimban-16-carboxylicacid, 17-hydroxy-, (16a,17a)-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Yohimban-16-carboxylicacid, 17-hydroxy-, (16a,17a)- |
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| CAS Number | 522-87-2 | Molecular Weight | 340.41600 |
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| Density | 1.39g/cm3 | Boiling Point | 600ºC at 760mmHg |
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| Molecular Formula | C20H24N2O3 | Melting Point | 267-268ºC (dec.)(lit.) |
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| MSDS | / | Flash Point | 316.6ºC |
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Names
| Name | yohimbic acid |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Yohimbic acid is an amphoteric demethylated derivative of Yohimbine. Yohimbic acid exhibits vasodilatory action, and has the potential for osteoarthritis (OA) research[1][2][3]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Wang S, et, al. Significantly dysregulated genes in osteoarthritic labrum cells identified through gene expression profiling. Mol Med Rep. 2019 Aug; 20(2): 1716-1724. [2]. HAMET R. [Sympatholytic activity and toxicity of an amphoteric demethylated derivative of yohimbine: yohimbic acid]. C R Hebd Seances Acad Sci. 1951 Oct 29;233(18):1069-71. [3]. HAMET R. [Demonstration of the direct vasodilatory action of yohimbic acid and Py-tetrahydroquinoline]. C R Hebd Seances Acad Sci. 1960 Jun 27;250:4473-5. |
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Chemical & Physical Properties
| Density | 1.39g/cm3 |
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| Boiling Point | 600ºC at 760mmHg |
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| Melting Point | 267-268ºC (dec.)(lit.) |
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| Molecular Formula | C20H24N2O3 |
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| Molecular Weight | 340.41600 |
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| Flash Point | 316.6ºC |
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| Exact Mass | 340.17900 |
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| PSA | 76.56000 |
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| LogP | 2.49660 |
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| Index of Refraction | 1.702 |
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| InChIKey | AADVZSXPNRLYLV-GKMXPDSGSA-N |
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| SMILES | O=C(O)C1C(O)CCC2CN3CCc4c([nH]c5ccccc45)C3CC21 |
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Safety Information
| Risk Phrases | 23/24/25 |
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| Safety Phrases | 26-28-36/37/39-45 |
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| RIDADR | UN 1544 6.1/PG 3 |
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| Packaging Group | II |
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| Hazard Class | 6.1(a) |
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Synonyms
| yohimbine acid |
| YOHIMBINIC ACID MONOHYDRATE |
| yohimbinic acid |
| YOHIMBIC ACID HYDRATE |
| YOHIMBIC ACID |
| Yohimbic |
| YOHIMBIC ACID MONOHYDRATE |
