CAS 1072-40-8|Hexaethylene glycol dimethyl ether

Introduction：Basic information about CAS 1072-40-8|Hexaethylene glycol dimethyl ether, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameHexaethylene glycol dimethyl ether
CAS Number1072-40-8Molecular Weight310.38400
Density1.02g/cm3Boiling Point359ºC at 760mmHg
Molecular FormulaC14H30O7Melting Point/
MSDS/Flash Point136.5ºC

Names

Name1-methoxy-2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethane
SynonymMore Synonyms

Hexaethylene glycol dimethyl ether BiologicalActivity

DescriptionHexaethylene glycol dimethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Density1.02g/cm3
Boiling Point359ºC at 760mmHg
Molecular FormulaC14H30O7
Molecular Weight310.38400
Flash Point136.5ºC
Exact Mass310.19900
PSA64.61000
LogP0.36220
Vapour Pressure5.08E-05mmHg at 25°C
Index of Refraction1.433

Safety Information

HS Code2901100000

Customs

HS Code2901100000
Summary2901100000 saturated acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

Synonyms

1,17-Dimethoxy-3,6,9,12,15-pentaoxa-heptadecan
2,5,8,11,14,17,20-heptaoxahenicosane
Hexaaethylenglykol-dimethylaether
2,5,8,11,14,17,20-Heptaoxaheneicosane
O,O'-Dimethyl-hexaaethylenglykol
Hexaethylene glycol dimethyl ether
1,17-dimethoxy-3,6,9,12,15-pentaoxa-heptadecane
EINECS 214-006-8
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