Introduction：Basic information about CAS 27591-97-5|Tilorone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tilorone |
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| CAS Number | 27591-97-5 | Molecular Weight | 410.549 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 552.3±50.0 °C at 760 mmHg |
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| Molecular Formula | C25H34N2O3 | Melting Point | / |
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| MSDS | / | Flash Point | 287.8±30.1 °C |
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Names
| Name | 2,7-bis[2-(diethylamino)ethoxy]fluoren-9-one |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 552.3±50.0 °C at 760 mmHg |
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| Molecular Formula | C25H34N2O3 |
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| Molecular Weight | 410.549 |
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| Flash Point | 287.8±30.1 °C |
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| Exact Mass | 410.256958 |
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| PSA | 42.01000 |
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| LogP | 5.25 |
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| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
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| Index of Refraction | 1.564 |
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| InChIKey | MPMFCABZENCRHV-UHFFFAOYSA-N |
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| SMILES | CCN(CC)CCOc1ccc2c(c1)C(=O)c1cc(OCCN(CC)CC)ccc1-2 |
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| Storage condition | -20°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- LL8990000
- CHEMICAL NAME :
- 9H-Fluoren-9-one, 2,7-bis(2-(diethylamino)ethoxy)-
- CAS REGISTRY NUMBER :
- 27591-97-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C25-H34-N2-O3
- MOLECULAR WEIGHT :
- 410.61
- WISWESSER LINE NOTATION :
- L B656 HVJ EO2N2&2 KO2N2&2
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1780 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 121 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Immunological Including Allergic - increased immune response Tumorigenic - active as anti-cancer agent
MUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 11,91,1975
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Synonyms
| UNII-O6W7VEW6KS |
| Tilorone |
| Amixin IC |
| 2,7-Bis-DEAE-fluorenone |
| Tilorone base |
| Tilorone hydrochloride |
| 2,7-Bis[2-(diethylamino)ethoxy]-9H-fluoren-9-one |
| 9H-Fluoren-9-one, 2,7-bis[2-(diethylamino)ethoxy]- |
| Bis-DEAE-fluorenone |
| 9H-Fluoren-9-one, 2,7-bis(2-(diethylamino)ethoxy)- |
| L B656 HVJ EO2N2&2 KO2N2&2 |
