CAS 14759-06-9|Thioridazine 2-Sulfone

Introduction:Basic information about CAS 14759-06-9|Thioridazine 2-Sulfone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameThioridazine 2-Sulfone
CAS Number14759-06-9Molecular Weight402.57300
Density1.221g/cm3Boiling Point589.1ºC at 760mmHg
Molecular FormulaC21H26N2O2S2Melting Point/
MSDS/Flash Point310.1ºC

Names

NameThioridazine 2-Sulfone
SynonymMore Synonyms

Chemical & Physical Properties

Density1.221g/cm3
Boiling Point589.1ºC at 760mmHg
Molecular FormulaC21H26N2O2S2
Molecular Weight402.57300
Flash Point310.1ºC
Exact Mass402.14400
PSA74.30000
LogP5.65090
Vapour Pressure7.45E-14mmHg at 25°C
Index of Refraction1.605
InChIKeyFLGCRGJDQJIJAW-UHFFFAOYSA-N
SMILESCN1CCCCC1CCN1c2ccccc2Sc2ccc(S(C)(=O)=O)cc21

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SP1925000
CHEMICAL NAME :
Phenothiazine, 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylsulfonyl-,
CAS REGISTRY NUMBER :
14759-06-9
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C21-H26-N2-O2-S2
MOLECULAR WEIGHT :
402.61
WISWESSER LINE NOTATION :
T C666 BN ISJ ESW1 B2- BT6NTJ A1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
24 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,53,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
520 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,53,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
138 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1596,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
29 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,53,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,53,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
18 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,53,1972

Safety Information

HS Code2934300000

Customs

HS Code2934300000
Summary2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfonylphenothiazine
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