CAS 27215-14-1|Neoandrographolide
| Common Name | Neoandrographolide | ||
|---|---|---|---|
| CAS Number | 27215-14-1 | Molecular Weight | 480.591 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 668.1±55.0 °C at 760 mmHg |
| Molecular Formula | C26H40O8 | Melting Point | 167-168ºC |
| MSDS | ChineseUSA | Flash Point | 220.1±25.0 °C |
Names
| Name | Neoandrographolide |
|---|---|
| Synonym | More Synonyms |
Neoandrographolide BiologicalActivity
| Description | Neoandrographolide is a diterpenoid from the Andrographis paniculata (Acanthaceae). |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>OthersNatural Products >>Terpenoids and Glycosides |
| References | [1]. Tao Yang, et al. Hypolipidemic Effects of Andrographolide and Neoandrographolide in Mice and Rats. Phytotherapy Research Volume 27, Issue 4, pages 618–623, April 2013 |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 668.1±55.0 °C at 760 mmHg |
| Melting Point | 167-168ºC |
| Molecular Formula | C26H40O8 |
| Molecular Weight | 480.591 |
| Flash Point | 220.1±25.0 °C |
| Exact Mass | 480.272308 |
| PSA | 125.68000 |
| LogP | 2.11 |
| Vapour Pressure | 0.0±4.6 mmHg at 25°C |
| Index of Refraction | 1.576 |
| InChIKey | YGCYRQKJYWQXHG-RDNQFMDVSA-N |
| SMILES | C=C1CCC2C(C)(COC3OC(CO)C(O)C(O)C3O)CCCC2(C)C1CCC1=CCOC1=O |
| Storage condition | 2-8C |
Safety Information
| RIDADR | NONH for all modes of transport |
|---|
Articles19
More Articles| Antihepatotoxic effects of major diterpenoid constituents of Andrographis paniculata. Biochem. Pharmacol. 46(1) , 182-5, (1993) The diterpenes andrographolide (I), andrographiside (II) and neoandrographolide (III) isolated from Andrographis paniculata were investigated for their protective effects on hepatotoxicity induced in ... | |
| Study of anti-inflammatory activities of the pure compounds from Andrographis paniculata (burm.f.) Nees and their effects on gene expression. Int. Immunopharmacol. 10(11) , 1361-73, (2010) In inflammation, the responses to noxious stimuli are controlled by the highly modulated interactions between various immune cells and chemical mediators. The purpose of this study is to evaluate and ... | |
| Quantitative analysis of four major diterpenoids in Andrographis paniculata by 1H NMR and its application for quality control of commercial preparations. J. Pharm. Biomed. Anal. 70 , 87-93, (2012) A quantitative proton nuclear magnetic resonance technique (qHNMR) has been successfully introduced to quantify andrographolide, dehydroandrographolide, deoxyandrographolide and neoandrographolide in ... |
Synonyms
| 2(5H)-Furanone, 3-[2-[(1R,4aS,5R,8aS)-5-[(β-D-glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]- |
| neo-Andrographolide |
| {(1R,4aS,5R,8aS)-1,4a-Dimethyl-6-methylene-5-[2-(2-oxo-2,5-dihydrofuran-3-yl)ethyl]decahydronaphthalen-1-yl}methyl β-D-glucopyranoside |
| {(1R,4aS,5R,8aS)-1,4a-Dimethyl-6-methylene-5-[2-(2-oxo-2,5-dihydro-3-furanyl)ethyl]decahydro-1-naphthalenyl}methyl β-D-glucopyranoside |
| neoandrographoside |
| Neoandrographolid |
| ANDROGRAPHOLIDE,NEO |
