Introduction：Basic information about CAS 7236-57-9|4-thiothymidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-thiothymidine |
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| CAS Number | 7236-57-9 | Molecular Weight | 258.29 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C10H14N2O4S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Thymidine, 4-thio |
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| Synonym | More Synonyms |
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4-thiothymidine BiologicalActivity
| Description | 4-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Molecular Formula | C10H14N2O4S |
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| Molecular Weight | 258.29 |
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| Exact Mass | 258.067413 |
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| PSA | 119.57000 |
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| LogP | -0.07 |
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| Index of Refraction | 1.672 |
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| InChIKey | AVKSPBJBGGHUMW-XLPZGREQSA-N |
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| SMILES | Cc1cn(C2CC(O)C(CO)O2)c(=O)[nH]c1=S |
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Safety Information
Synonyms
| deoxy-4-thiothymidine |
| 4-thio-thymidine |
| 4-Thio-thymidin |
| 2(1H)-Pyrimidinone, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-3,4-dihydro-5-methyl-4-thioxo- |
| 4-thiothymidine |
| 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-methyl-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone |
