CAS 280-57-9|DABCO
Introduction：Basic information about CAS 280-57-9|DABCO, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | DABCO | ||
|---|---|---|---|
| CAS Number | 280-57-9 | Molecular Weight | 112.17 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 174.0±0.0 °C at 760 mmHg |
| Molecular Formula | C6H12N2 | Melting Point | 156-159 °C(lit.) |
| MSDS | Chinese | Flash Point | 62.2±0.0 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | Triethylenediamine |
|---|---|
| Synonym | More Synonyms |
DABCO BiologicalActivity
| Description | 1,4-Diazabicyclo[2.2.2]octane is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
|---|---|
| Related Catalog | Research Areas >>Others |
| In Vitro | 1,4-二氮杂双环[2.2.2]辛烷用作聚氨酯催化剂，Balis-Hillman反应催化剂络合配体和路易斯碱。它可用于染料激光器和荧光显微镜的样品镶嵌，以及作为抗褪色剂显示可清除由于荧光染料激发荧光染料而产生的 Venge 自由基。此外，它还是一种氧化和聚合催化剂。 |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 174.0±0.0 °C at 760 mmHg |
| Melting Point | 156-159 °C(lit.) |
| Molecular Formula | C6H12N2 |
| Molecular Weight | 112.17 |
| Flash Point | 62.2±0.0 °C |
| Exact Mass | 112.100044 |
| PSA | 6.48000 |
| LogP | -0.85 |
| Vapour Pressure | 1.2±0.3 mmHg at 25°C |
| Index of Refraction | 1.561 |
| InChIKey | IMNIMPAHZVJRPE-UHFFFAOYSA-N |
| SMILES | C1CN2CCN1CC2 |
| Storage condition | 2-8°C |
| Stability | Stable, but very hygroscopic. Incompatible with strong oxidizing agents, strong acids. Highly flammable. |
| Water Solubility | 46 g/100 mL (26 ºC) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 4,522,1962
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 4,522,1962 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ZHYGAM Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1955- Volume(issue)/page/year: 20,393,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1100 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - muscle contraction or spasticity
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 45(5),67,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 2250 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - muscle contraction or spasticity
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 45(5),67,1980 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4680 mg/kg/26W-I
- TOXIC EFFECTS :
- Behavioral - alteration of classical conditioning Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 45(5),67,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0905 No. of Facilities: 334 (estimated) No. of Industries: 9 No. of Occupations: 15 No. of Employees: 1710 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0905 No. of Facilities: 1104 (estimated) No. of Industries: 23 No. of Occupations: 30 No. of Employees: 33913 (estimated) No. of Female Employees: 5787 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335-H412 |
| Precautionary Statements | P261-P273-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | F:Flammable |
| Risk Phrases | R11;R22;R36/38;R41;R52/53 |
| Safety Phrases | S26-S60-S37/39-S3-S16-S36/37 |
| RIDADR | UN 1325 4.1/PG 2 |
| WGK Germany | 1 |
| RTECS | HM0354200 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 29335920 |
Customs
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| T66 A B CN FNTJ |
| UNII-X8M57R0JS5 |
| 1,4-diazabicyclo-[2.2.2]octane |
| dabco33lv |
| 1,4-Diazabicyclo[2.2.2]octane |
| 1,4-diazabicyclo-[2.2.2]-octane |
| DABCO |
| TEDA-L33 |
| diazabicyclooctane |
| 1,4-diazabicyclo(2.2.2) octane |
| TED |
| BACO |
| 1,4-diaza-bicyclo[2.2.2]octane |
| teda |
| triethylenediamine |
| Triethylene diamine |
| dabcoeg |
| EINECS 205-999-9 |
| MFCD00006689 |
| dabcos-25 |
