CAS 66215-27-8|Cyromazine

Introduction：Basic information about CAS 66215-27-8|Cyromazine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Cyromazine BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Articles27
8. Synonyms

Common Name	Cyromazine
CAS Number	66215-27-8	Molecular Weight	166.184
Density	1.6±0.1 g/cm3	Boiling Point	480.6±28.0 °C at 760 mmHg
Molecular Formula	C₆H₁₀N₆	Melting Point	223-227 °C(lit.)
MSDS	ChineseUSA	Flash Point	244.5±24.0 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	cyromazine
Synonym	More Synonyms

Cyromazine BiologicalActivity

Description	Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease
References	[1]. Levot GW, et al. Survival advantage of cyromazine-resistant sheep blowfly larvae on dicyclanil- and cyromazine-treated Merinos. Aust Vet J. 2014 Nov;92(11):421-6. [2]. Levot GW, et al. Survival advantage of cyromazine-resistant sheep blowfly larvae on dicyclanil- and cyromazine-treated Merinos. Aust Vet J. 2014 Nov;92(11):421-6.

Description

Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.

Related Catalog

Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease

References

[1]. Levot GW, et al. Survival advantage of cyromazine-resistant sheep blowfly larvae on dicyclanil- and cyromazine-treated Merinos. Aust Vet J. 2014 Nov;92(11):421-6.

[2]. Levot GW, et al. Survival advantage of cyromazine-resistant sheep blowfly larvae on dicyclanil- and cyromazine-treated Merinos. Aust Vet J. 2014 Nov;92(11):421-6.

Chemical & Physical Properties

Density	1.6±0.1 g/cm3
Boiling Point	480.6±28.0 °C at 760 mmHg
Melting Point	223-227 °C(lit.)
Molecular Formula	C₆H₁₀N₆
Molecular Weight	166.184
Flash Point	244.5±24.0 °C
Exact Mass	166.096695
PSA	102.74000
LogP	-0.04
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.851
InChIKey	LVQDKIWDGQRHTE-UHFFFAOYSA-N
SMILES	Nc1nc(N)nc(NC2CC2)n1
Storage condition	0-6°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XZ1056500

CHEMICAL NAME :: 1,3,5-Triazine-2,4,6-triamine, N-cyclopropyl-

CAS REGISTRY NUMBER :: 66215-27-8

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C6-H10-N6

MOLECULAR WEIGHT :: 166.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3387 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,217,1991

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2720 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,217,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >3100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,217,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: 1785 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,217,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: >6 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C91,1991

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	XZ1056500
HS Code	2933699015

Customs

HS Code	2933699015
Summary	2933699015 4,6-dichloro-n-(2-chlorophenyl)-1,3,5-triazin-2-amine。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

Articles27

Validation of a rapid method of analysis using ultrahigh-performance liquid chromatography - tandem mass spectrometry for nitrogen-rich adulterants in nutritional food ingredients.

J. Chromatogr. A. 1373 , 106-13, (2014)

A method for the rapid quantification of 9 potential nitrogen-rich economic adulterants (dicyandiamide, urea, biuret, cyromazine, amidinourea, ammeline, amidinourea, melamine, and cyanuric acid) in fi...

Inheritance mode, cross-resistance and realized heritability of pyriproxyfen resistance in a field strain of Musca domestica L. (Diptera: Muscidae).

Acta Trop. 142 , 149-55, (2014)

Pyriproxyfen is a growth regulator used for the control of different insect pests, including Musca domestica. To assess the risk of resistance and to develop a strategy for resistance management, a fi...

A novel colloidal gold-based lateral flow immunoassay for rapid simultaneous detection of cyromazine and melamine in foods of animal origin.

Food Chem. 138(2-3) , 1610-5, (2013)

A rapid and sensitive lateral flow immunoassay (LFIA) based on competitive format was developed and validated for simultaneous detection of cyromazine (CA) and melamine (MA) in foods of animal origin....

Synonyms

2-N-cyclopropyl-1,3,5-triazine-2,4,6-triamine

Larvadex

Vetrazine

N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine

EINECS 266-257-8

N-Cyclopropyl-1,3,5-triazine-2,4,6-triamine

Vetrazin

2,4-diamino-6-cyclopropylamino-1,3,5-triazine

Azimethiphos

MFCD00078650

Neporex

2,4-diamino-6-cyclopropylamino-s-triazine

Cyromazine

1,3,5-Triazine-2,4,6-triamine, N-cyclopropyl-

N1-cyclopropyl-1,3,5-triazine-2,4,6-triamine

Cyclopropylmelamine

Cypromazine

Citation

Trigard

N CYCLOPROPYL 1,3,5 TRIAZINE 2,4,6 TRIAMINE

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