CAS 27605-76-1|3-(Allyloxy)-1,2-benzothiazole 1,1-dioxide

Introduction：Basic information about CAS 27605-76-1|3-(Allyloxy)-1,2-benzothiazole 1,1-dioxide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles19
7. Synonyms

Common Name	3-(Allyloxy)-1,2-benzothiazole 1,1-dioxide
CAS Number	27605-76-1	Molecular Weight	223.248
Density	1.3±0.1 g/cm3	Boiling Point	369.0±35.0 °C at 760 mmHg
Molecular Formula	C₁₀H₉NO₃S	Melting Point	139 °C
MSDS	USA	Flash Point	177.0±25.9 °C

Names

Name	probenazole
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	369.0±35.0 °C at 760 mmHg
Melting Point	139 °C
Molecular Formula	C₁₀H₉NO₃S
Molecular Weight	223.248
Flash Point	177.0±25.9 °C
Exact Mass	223.030319
PSA	64.11000
LogP	1.87
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.604
InChIKey	WHHIPMZEDGBUCC-UHFFFAOYSA-N
SMILES	C=CCOC1=NS(=O)(=O)c2ccccc21

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DE4155000

CHEMICAL NAME :: 1,2-Benzisothiazole, 3-(allyloxy)-, 1,1-dioxide

CAS REGISTRY NUMBER :: 27605-76-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C10-H9-N-O3-S

MOLECULAR WEIGHT :: 223.26

WISWESSER LINE NOTATION :: T56 BSWNJ DO2U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2030 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 7,307,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 850 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 13,219,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (37),37,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2750 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 13,205,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 745 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 13,205,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (37),37,1980

Safety Information

Hazard Codes	Xn,Xi
Risk Phrases	R22:Harmful if swallowed. R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases	S36/37
RIDADR	3276
WGK Germany	3
Packaging Group	III
Hazard Class	6.1
HS Code	2934200013

Customs

HS Code	2934200013
Summary	2934200013 3-(allyloxy)benzo[d]isothiazole 1,1-dioxide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

Articles19

Characterization of PBZ1, a probenazole-inducible gene, in suspension-cultured rice cells.

Biosci. Biotechnol. Biochem. 65(1) , 205-8, (2001)

Probenazole (PBZ) induces non-race specific resistance in rice plants against rice blast fungus and PBZ1 was identified as a PBZ-inducible gene from rice. The induction of PBZ1 expression in suspensio...

Different responses of two genes associated with disease resistance loci in maize (Zea mays L.) to 3-allyloxy-1,2-benzothiazole 1,1-dioxide.

Curr. Issues Mol. Biol. 11 Suppl 1 , i85-94, (2009)

Probenazole (3-allyloxy-1,2-benzothiazole 1,1-dioxide, PBZ) is a bactericide and fungicide that acts by inducing plant defense systems. It has been shown to induce the expression of NBS-LRR genes like...

Proteome analysis of probenazole-effect in rice-bacterial blight interactions.

Protein Pept. Lett. 16(9) , 1041-52, (2009)

To study the effect of probenazole on the induced systemic resistance mechanism of rice-bacterial interaction, a proteomic approach was applied. Oryza sativa cv. Java 14 seedlings were treated with pr...

Synonyms

3-allyloxy-1,2-benzisothiazole-1,1-dioxide

3-(2-Propenyloxy)-1,2-benzisothiazole 1,1-dioxide,3-Allyloxy-1,2-benzisothiazole 1,1-dioxide

Probenazole Standard

3-(Prop-2-en-1-yloxy)-1,2-benzisothiazole 1,1-dioxide

3-(prop-2-en-1-yloxy)-1λ6,2-benzothiazole-1,1-dione

ORYZEMATE

oryzaemate

MFCD00274602

1,2-Benzisothiazole, 3-(2-propen-1-yloxy)-, 1,1-dioxide

po-20

1,2-Benzisothiazole, 3-(2-propenyloxy)-, 1,1-dioxide (9CI)

3-(Allyloxy)-1,2-benzothiazole 1,1-dioxide

3-Allyloxy-1,2-benz[d]isothiazole 1,1-dioxide

3-(allyloxy)-1,2-benzisothiazole 1,1-dioxide

3-allyloxy-1,2-benzothiazole 1,1-dioxide

ORYZAMATE

Probenazole

3-(Allyloxy)benzo[d]isothiazole 1,1-dioxide

3-(2-Propèn-1-yloxy)-1,2-benzothiazole-1,1-dioxyde

PROBENAZOIE

3-(2-propen-1-yloxy)-1,2-benzisothiazole 1,1-dioxide

3-(Prop-2-en-1-yloxy)-1,2-benzisothiazol-1,1-dioxid

3-(prop-2-en-1-yloxy)-1,2-benzothiazole 1,1-dioxide

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