CAS 53112-28-0|pyrimethanil

Introduction:Basic information about CAS 53112-28-0|pyrimethanil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namepyrimethanil
CAS Number53112-28-0Molecular Weight199.252
Density1.1±0.1 g/cm3Boiling Point362.8±45.0 °C at 760 mmHg
Molecular FormulaC12H13N3Melting Point96°C
MSDSChineseUSAFlash Point173.2±28.7 °C
Symbol
GHS09
Signal Word

Names

Namepyrimethanil
SynonymMore Synonyms

pyrimethanil BiologicalActivity

DescriptionPyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection[3].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>Fungal
In VitroPyrimethanil is a strobilurin fungicide belonging to the anilinopyrimidine class. Pyrimethanil (5 and 50 µg/L) elicits a range of toxic responses, has the potential to induce histological alterations in tissues of the Italian tree frog H. intermedia after a long term exposure to two environmentally relevant concentrations of Pyrimethanil[2]. Pyrimethanil decreases polygalacturonase, cellulase, proteinase and laccase activities in the medium of three day‐old cultures. The pyrimethanil results in 50% reduction (IC50) in total enzyme activities are approximately 0.25 μM for polygalacturonase, cellulase and proteinase, and approximately 1.0 μM for laccase[3].
References

[1]. Petr Masner, et al. Possible methionine biosynthesis inhibition by pyrimidinamine fungicides. Pesticide Science

[2]. L Kanetis, et al. Characterization of genetic and biochemical mechanisms of fludioxonil and pyrimethanil resistance in field isolates of Penicillium digitatum. Phytopathology

[3]. Richard J. Milling, et al. Mode of action of the anilino‐pyrimidine fungicide pyrimethanil. 2. Effects on enzyme secretion in Botrytis cinerea. Volume45, Issue1, September 1995.

[4]. Salvatore D'Aquino, et al. Residue levels and effectiveness of pyrimethanil vs imazalil when using heated postharvest dip treatments for control of Penicillium decay on citrus fruit. J Agric Food Chem. 2006 Jun 28;54(13):4721-6.

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point362.8±45.0 °C at 760 mmHg
Melting Point96°C
Molecular FormulaC12H13N3
Molecular Weight199.252
Flash Point173.2±28.7 °C
Exact Mass199.110947
PSA37.81000
LogP2.84
Vapour Pressure0.0±0.8 mmHg at 25°C
Index of Refraction1.622
InChIKeyZLIBICFPKPWGIZ-UHFFFAOYSA-N
SMILESCc1cc(C)nc(Nc2ccccc2)n1
Storage condition0-6°C
Water Solubility0.121 g/L (25 ºC)

Safety Information

Symbol
GHS09
Hazard StatementsH411
Precautionary StatementsP273
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesN:Dangerousfortheenvironment;
Risk PhrasesR51/53
Safety PhrasesS60
RIDADRUN 3077
HS Code2942000000

Customs

HS Code2933599014
Summary2933599014 6-nitroso-7h-purine。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

Articles27

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Postinfection activity, residue levels, and persistence of azoxystrobin, fludioxonil, and pyrimethanil applied alone or in combination with heat and imazalil for green mold control on inoculated oranges.

J. Agric. Food Chem. 58(6) , 3661-6, (2010)

The postinfection activity of azoxystrobin (AZX), fludioxonil (FLU), and pyrimethanil (PYR), applied alone or in combination with imazalil (IMZ), in controlling postharvest green mold in 'Salustiana' ...

Determination of natural resistance frequencies in Penicillium digitatum using a new air-sampling method and characterization of fludioxonil- and pyrimethanil-resistant isolates.

Phytopathology 100(8) , 738-46, (2010)

ABSTRACT Fungicide resistance was identified in natural populations of Penicillium digitatum, the causal agent of green mold of citrus, to two of three new postharvest fungicides before their commerci...

Synonyms

4,6-Dimethyl-N-phenyl-2-pyrimidinamine
4,6-dimethyl-n-phenyl-2-pyrimidinamin
N-(4,6-dimethylpyrimidin-2-yl)aniline
EINECS 414-220-3
2-Pyrimidinamine,4,6-dimethyl-N-phenyl
4,6-dimethyl-N-phenylpyrimidin-2-amine
4,6-dimethylpyrimidine-N-phenylimine
2-anilino-4,6-dimethylpyrimidine
MFCD00172113
Pyrimethanil
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