CAS 110-15-6|Succinic acid
Introduction：Basic information about CAS 110-15-6|Succinic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Succinic acid | ||
|---|---|---|---|
| CAS Number | 110-15-6 | Molecular Weight | 118.088 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 236.1±13.0 °C at 760 mmHg |
| Molecular Formula | C4H6O4 | Melting Point | 185 °C |
| MSDS | ChineseUSA | Flash Point | 110.9±16.3 °C |
| Symbol | GHS05 | Signal Word | Danger |
Names
| Name | succinic acid |
|---|---|
| Synonym | More Synonyms |
Succinic acid BiologicalActivity
| Description | Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism. |
|---|---|
| Related Catalog | Natural Products >>Acids and AldehydesResearch Areas >>Metabolic Disease |
| Target | Human Endogenous Metabolite |
| References | [1]. Zhang YJ, et al. Optimization of succinic acid fermentation with Actinobacillus succinogenes by response surface methodology (RSM). J Zhejiang Univ Sci B. 2012 Feb;13(2):103-10. |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 236.1±13.0 °C at 760 mmHg |
| Melting Point | 185 °C |
| Molecular Formula | C4H6O4 |
| Molecular Weight | 118.088 |
| Flash Point | 110.9±16.3 °C |
| Exact Mass | 118.026611 |
| PSA | 74.60000 |
| LogP | -0.59 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.478 |
| InChIKey | KDYFGRWQOYBRFD-UHFFFAOYSA-N |
| SMILES | O=C(O)CCC(=O)O |
| Storage condition | Store at RT. |
| Stability | Stable. Substances to be avoided include strong bases, strong oxidizing agents. Combustible. |
| Water Solubility | 80 g/L (20 ºC) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2260 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2702 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Fibroblast
- DOSE/DURATION :
- 20 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 183,89,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84381 No. of Facilities: 316 (estimated) No. of Industries: 18 No. of Occupations: 21 No. of Employees: 3351 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84381 No. of Facilities: 1652 (estimated) No. of Industries: 16 No. of Occupations: 38 No. of Employees: 31198 (estimated) No. of Female Employees: 16182 (estimated)
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Fibroblast
- DOSE/DURATION :
- 20 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 183,89,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84381 No. of Facilities: 316 (estimated) No. of Industries: 18 No. of Occupations: 21 No. of Employees: 3351 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84381 No. of Facilities: 1652 (estimated) No. of Industries: 16 No. of Occupations: 38 No. of Employees: 31198 (estimated) No. of Female Employees: 16182 (estimated)
Safety Information
| Symbol | GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H318 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36/37/39-S37/39 |
| RIDADR | UN 3265 8/PG 3 |
| WGK Germany | 1 |
| RTECS | WM4900000 |
| Hazard Class | 8.0 |
| HS Code | 2917190090 |
Customs
| HS Code | 2917190090 |
|---|---|
| Summary | 2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| MFCD00002789 |
| Butane diacid |
| Butanedioic acid,natural |
| HOOC-CH2-CH2-COOH |
| 4-02-00-01908 (Beilstein Handbook Reference) |
| Bernsteinsaure [German] |
| Succinic acid |
| 1,4-Butanedioic acid |
| 1,2-Ethanedicarboxylic acid |
| Sal succini |
| QV2VQ |
| Succinic acid |
| Butanedioic acid |
| Asuccin |
| Katasuccin |
| Wormwood |
| EINECS 203-740-4 |
| spirit of amber |
| AMBER ACID |
