CAS 10523-68-9|2-adamantaneamine hydrochloride

Introduction：Basic information about CAS 10523-68-9|2-adamantaneamine hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles5
7. Synonyms

Common Name	2-adamantaneamine hydrochloride
CAS Number	10523-68-9	Molecular Weight	187.710
Density	/	Boiling Point	226.1ºC at 760 mmHg
Molecular Formula	C₁₀H₁₈ClN	Melting Point	>300 °C(lit.)
MSDS	ChineseUSA	Flash Point	96.5ºC
Symbol	GHS07	Signal Word	Warning

Names

Name	2-Adamantanamine hydrochloride
Synonym	More Synonyms

Chemical & Physical Properties

Boiling Point	226.1ºC at 760 mmHg
Melting Point	>300 °C(lit.)
Molecular Formula	C₁₀H₁₈ClN
Molecular Weight	187.710
Flash Point	96.5ºC
Exact Mass	187.112778
PSA	26.02000
LogP	3.27210
Vapour Pressure	0.0831mmHg at 25°C
InChIKey	WLDWDRZITJEWRJ-UHFFFAOYSA-N
SMILES	Cl.NC1C2CC3CC(C2)CC1C3
Water Solubility	soluble

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU4375100

CHEMICAL NAME :: 2-Adamantanamine, hydrochloride

CAS REGISTRY NUMBER :: 10523-68-9

LAST UPDATED :: 198506

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H17-N.Cl-H

MOLECULAR WEIGHT :: 187.74

WISWESSER LINE NOTATION :: L66 B6/B-H/DI A B- C 1B ITJ AZ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Behavioral - anticonvulsant

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 14,313,1980

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R36/37/38
Safety Phrases	S26-S36-S36/37/39-S22
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	AU4375100
HS Code	2921300090

Customs

HS Code	2921300090
Summary	2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles5

Modification of the antibiotic olivomycin I at the 2'-keto group of the side chain. Novel derivatives, antitumor and topoisomerase I-poisoning activity.

J. Antibiot. 62(1) , 37-41, (2009)

A novel way of chemical modification of the antibiotic olivomycin I at the 2'-keto group of the side chain of the aglycone moiety was developed. Reaction of olivomycin I with the carboxymethoxylamine ...

Simultaneous liquid chromatographic assay of amantadine and its four related compounds in phosphate-buffered saline using 4-fluoro-7-nitro-2,1,3-benzoxadiazole as a fluorescent derivatization reagent.

Biomed. Chromatogr. 20(5) , 423-8, (2006)

Simultaneous HPLC assay of 1-adamantanamine hydrochloride (amantadine) and its four related compounds [2-adamantanamine hydrochloride (2-ADA), 1-adamantanmethylamine (ADAMA), 1-(1-adamantyl)ethylamine...

[A quantitative pharmaco-electroencephalographic analysis of the action of bromantane].

Biull. Eksp. Biol. Med. 116(11) , 515-8, (1993)

The action of the new stimulant bromantane on spectra power EEG on Fourier of sensorimotor cortex, dorsal hippocamp and lateral hypothalamus of left and right hemispheres of brain of rat in free behav...

Synonyms

Adamantan-2-amine hydrochloride (1:1)

2-adamantaneamine hydrochloride

Tricyclo[3.3.1.1]decan-2-amine, hydrochloride (1:1)

MFCD00074743

2-Adamantanamine hydrochloride (1:1)

2-Aminoadamantane Hydrochloride

Adamantan-2-amine hydrochloride

EINECS 234-074-2

adamantan-2-amine,hydrochloride

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