CAS 109-06-8|2-picoline
Introduction：Basic information about CAS 109-06-8|2-picoline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-picoline | ||
|---|---|---|---|
| CAS Number | 109-06-8 | Molecular Weight | 93.127 |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 127.5±3.0 °C at 760 mmHg |
| Molecular Formula | C6H7N | Melting Point | −70 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 26.1±0.0 °C |
| Symbol | GHS02, GHS06 | Signal Word | Danger |
Names
| Name | 2-methylpyridine |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 127.5±3.0 °C at 760 mmHg |
| Melting Point | −70 °C(lit.) |
| Molecular Formula | C6H7N |
| Molecular Weight | 93.127 |
| Flash Point | 26.1±0.0 °C |
| Exact Mass | 93.057846 |
| PSA | 12.89000 |
| LogP | 1.19 |
| Vapour density | 3.2 (vs air) |
| Vapour Pressure | 13.5±0.2 mmHg at 25°C |
| Index of Refraction | 1.501 |
| InChIKey | BSKHPKMHTQYZBB-UHFFFAOYSA-N |
| SMILES | Cc1ccccn1 |
| Stability | Stable. Flammable. Incompatible with strong oxidizing agents, sulfuric acid, acids, metals, iron (II) sulfate, hydrogen peroxide. Hygroscopic. |
| Water Solubility | MISCIBLE |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 790 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4000 ppm/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 674 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 9 gm/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 529 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 410 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1072 mg/kg/9W-I
- TOXIC EFFECTS :
- Blood - change in clotting factors Blood - thrombocytopenia Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1810 ug/kg/26W-I
- TOXIC EFFECTS :
- Blood - change in clotting factors Blood - changes in other cell count (unspecified) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
MUTATION DATA - TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TEST SYSTEM :
- Yeast - Saccharomyces cerevisiae
- DOSE/DURATION :
- 7400 ppm
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 163,23,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3811 No. of Facilities: 132 (estimated) No. of Industries: 6 No. of Occupations: 8 No. of Employees: 11240 (estimated) No. of Female Employees: 1234 (estimated)
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TEST SYSTEM :
- Yeast - Saccharomyces cerevisiae
- DOSE/DURATION :
- 7400 ppm
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 163,23,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3811 No. of Facilities: 132 (estimated) No. of Industries: 6 No. of Occupations: 8 No. of Employees: 11240 (estimated) No. of Female Employees: 1234 (estimated)
Safety Information
| Symbol | GHS02, GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H226-H302 + H332-H311-H319-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338-P312 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R10;R20/21/22;R36/37 |
| Safety Phrases | S26-S36 |
| RIDADR | UN 2313 3/PG 3 |
| WGK Germany | 1 |
| RTECS | TJ4900000 |
| Packaging Group | III |
| Hazard Class | 3 |
| HS Code | 29333999 |
Customs
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| a-Picoline |
| 2-picoline |
| methylpyridine |
| ALPHAP |
| 2-Methylpyridine |
| MFCD00006332 |
| 2-Methyl pyridine |
| aPicolin |
| ai3-2409 |
| 2-methyl-pyridine |
| α-Picoline |
| monomethylpyridine |
| EINECS 203-643-7 |
| Pyridine, 2-methyl- |
| o-Picoline |
