CAS 627-93-0|Dimethyl adipate

Introduction：Basic information about CAS 627-93-0|Dimethyl adipate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles8
7. Synonyms

Common Name	Dimethyl adipate
CAS Number	627-93-0	Molecular Weight	174.194
Density	1.0±0.1 g/cm3	Boiling Point	228.7±0.0 °C at 760 mmHg
Molecular Formula	C₈H₁₄O₄	Melting Point	8 °C(lit.)
MSDS	ChineseUSA	Flash Point	107.2±0.0 °C

Names

Name	Dimethyl adipate
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	228.7±0.0 °C at 760 mmHg
Melting Point	8 °C(lit.)
Molecular Formula	C₈H₁₄O₄
Molecular Weight	174.194
Flash Point	107.2±0.0 °C
Exact Mass	174.089203
PSA	52.60000
LogP	1.03
Vapour Pressure	0.1±0.4 mmHg at 25°C
Index of Refraction	1.423
InChIKey	UDSFAEKRVUSQDD-UHFFFAOYSA-N
SMILES	COC(=O)CCCCC(=O)OC
Stability	Stable. Combustible. Incompatible with strong oxidizing agents, acids, bases reducing agents.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AV1645000

CHEMICAL NAME :: Adipic acid, dimethyl ester

CAS REGISTRY NUMBER :: 627-93-0

BEILSTEIN REFERENCE NO. :: 1707443

LAST UPDATED :: 199712

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C8-H14-O4

MOLECULAR WEIGHT :: 174.22

WISWESSER LINE NOTATION :: 1OV4VO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1809 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 62,1596,1973 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 362 mg/kg

SEX/DURATION :: female 5-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 62,1596,1973

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 181 mg/kg

SEX/DURATION :: female 5-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 62,1596,1973 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1493 No. of Facilities: 2425 (estimated) No. of Industries: 18 No. of Occupations: 25 No. of Employees: 24766 (estimated) No. of Female Employees: 3381 (estimated)

Safety Information

Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	Xi
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	AV1645000
HS Code	29171290

Customs

HS Code	2917120090
Summary	2917120090. adipic acid and its salts. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Articles8

Mixture risk assessment: a case study of Monsanto experiences.

Food Chem. Toxicol. 34(11-12) , 1139-45, (1996)

Monsanto employs several pragmatic approaches for evaluating the toxicity of mixtures. These approaches are similar to those recommended by many national and international agencies. When conducting ha...

Carboxylesterase-dependent cytotoxicity of dibasic esters (DBE) in rat nasal explants.

Toxicol. Appl. Pharmacol. 107(2) , 285-301, (1991)

Dibasic esters (DBE) are a solvent mixture of dimethyl adipate (DMA), dimethyl glutarate (DMG), and dimethyl succinate (DMS) used in the paint and coating industry. Subchronic inhalation toxicity stud...

Metabolism of dibasic esters by rat nasal mucosal carboxylesterase.

Drug Metab. Dispos. 19(1) , 124-9, (1991)

Inhalation exposure of rats to dibasic esters revealed lesions of the nasal olfactory epithelium similar to those observed with other ester solvents. Female rats are more sensitive to these effects th...

Synonyms

EINECS 211-020-6

MFCD00008469

dimethyl hexanedioate

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