CAS 2489-77-2|trimethylthiourea

CHEMICAL IDENTIFICATION

RTECS NUMBER :

YU4900000

CHEMICAL NAME :

Urea, 1,1,3-trimethyl-2-thio-

CAS REGISTRY NUMBER :

2489-77-2

LAST UPDATED :

199701

DATA ITEMS CITED :

9

MOLECULAR FORMULA :

C4-H10-N2-S

MOLECULAR WEIGHT :

118.22

WISWESSER LINE NOTATION :

SUYM1&N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

316 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

215 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

13 gm/kg/77W-C

TOXIC EFFECTS :

Tumorigenic - Carcinogenic by RTECS criteria Endocrine - thyroid tumors

MUTATION DATA

TYPE OF TEST :

Mutation in mammalian somatic cells

TEST SYSTEM :

Rodent - mouse Lymphocyte

DOSE/DURATION :

4200 mg/L

REFERENCE :

EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 12,85,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82038 No. of Facilities: 36 (estimated) No. of Industries: 1 No. of Occupations: 13 No. of Employees: 1063 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82038 No. of Facilities: 60 (estimated) No. of Industries: 2 No. of Occupations: 13 No. of Employees: 1521 (estimated) No. of Female Employees: 52 (estimated)