CAS 17420-30-3|2-Cyano-4-nitroaniline

Introduction：Basic information about CAS 17420-30-3|2-Cyano-4-nitroaniline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles4
7. Synonyms

Common Name	2-Cyano-4-nitroaniline
CAS Number	17420-30-3	Molecular Weight	163.133
Density	1.4±0.1 g/cm3	Boiling Point	383.2±32.0 °C at 760 mmHg
Molecular Formula	C₇H₅N₃O₂	Melting Point	200-207 °C(lit.)
MSDS	ChineseUSA	Flash Point	185.6±25.1 °C

Names

Name	5-Nitroanthranilonitrile
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	383.2±32.0 °C at 760 mmHg
Melting Point	200-207 °C(lit.)
Molecular Formula	C₇H₅N₃O₂
Molecular Weight	163.133
Flash Point	185.6±25.1 °C
Exact Mass	163.038177
PSA	95.63000
LogP	1.64
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.627
InChIKey	MGCGMYPNXAFGFA-UHFFFAOYSA-N
SMILES	N#Cc1cc([N+](=O)[O-])ccc1N

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BX2500000

CHEMICAL NAME :: Aniline, 2-cyano-4-nitro-

CAS REGISTRY NUMBER :: 17420-30-3

BEILSTEIN REFERENCE NO. :: 1425714

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C7-H5-N3-O2

MOLECULAR WEIGHT :: 163.15

WISWESSER LINE NOTATION :: WNR DZ CCN

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3884 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,924,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6710 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 30(1),50,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 34500 mg/kg/30D-I

TOXIC EFFECTS :: Liver - liver function tests impaired Liver - changes in liver weight Blood - other changes

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 30(1),50,1986

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn:Harmful
Risk Phrases	R20/21/22
Safety Phrases	S22-S24/25-S36
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	BX2500000
Packaging Group	I; II; III
Hazard Class	6.1
HS Code	2926909090

Customs

HS Code	2926909090
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles4

Design, Synthesis, and Biological Evaluation of Novel Quinazoline Derivatives as Anti-inflammatory Agents against Lipopolysaccharide-induced Acute Lung Injury in Rats.

Chem. Biol. Drug Des. 85 , 672-84, (2015)

Quinazoline has been reported to exhibit multiple bioactivities. The aim of this study was to discover new quinazoline derivatives with preventive effect on lipopolysaccharide-induced acute lung injur...

SERRS dyes. Part 3. Synthesis of reactive benzotriazole azo dyes for surface enhanced resonance Raman scattering.

Analyst 129(10) , 975-8, (2004)

A series of eleven specially designed benzotriazole monoazo dyes for use in surface enhanced resonance Raman scattering studies are reported. Unlike previous benzotriazole dyes produced for SERRS, the...

Synthesis and biological evaluation of 3,5-diaminoindazoles as cyclin-dependent kinase inhibitors.

Bioorg. Med. Chem. Lett. 18(7) , 2292-5, (2008)

A novel series of 3,5-diaminoindazoles were prepared and found to be CDK inhibitors. Potent inhibitors against CDK1 and CDK2 were obtained by introduction of 1lambda(6)-isothiazolidine-1,1-dioxide at ...

Synonyms

Anthranilonitrile, 5-nitro-

EINECS 241-446-8

MFCD00007362

2-Amino-5-nitrobenzonitrile

Benzonitrile, 2-amino-5-nitro-

2-Cyano-4-nitroaniline

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