Introduction：Basic information about CAS 72025-60-6|Leukotriene C4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Leukotriene C4 |
|---|
| CAS Number | 72025-60-6 | Molecular Weight | 625.774 |
|---|
| Density | 1.2±0.1 g/cm3 | Boiling Point | 974.3±65.0 °C at 760 mmHg |
|---|
| Molecular Formula | C30H47N3O9S | Melting Point | / |
|---|
| MSDS | / | Flash Point | 543.1±34.3 °C |
|---|
Names
| Name | leukotriene C4 |
|---|
| Synonym | More Synonyms |
|---|
Leukotriene C4 BiologicalActivity
| Description | Leukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. Leukotriene C4 is produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets. Leukotriene C4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity. |
|---|
| Target | Human Endogenous Metabolite |
|---|
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|
| Boiling Point | 974.3±65.0 °C at 760 mmHg |
|---|
| Molecular Formula | C30H47N3O9S |
|---|
| Molecular Weight | 625.774 |
|---|
| Flash Point | 543.1±34.3 °C |
|---|
| Exact Mass | 625.303284 |
|---|
| PSA | 241.65000 |
|---|
| LogP | 4.35 |
|---|
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
|---|
| Index of Refraction | 1.564 |
|---|
| InChIKey | GWNVDXQDILPJIG-NXOLIXFESA-N |
|---|
| SMILES | CCCCCC=CCC=CC=CC=CC(SCC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(=O)O)C(O)CCCC(=O)O |
|---|
Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- MB9143500
- CHEMICAL NAME :
- Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecat etraenyl)-N-L-gamma-g lutamyl-L- cysteinyl)-, (R-(R*,S*-(E,E,Z,Z)))-
- CAS REGISTRY NUMBER :
- 72025-60-6
- LAST UPDATED :
- 198912
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C30-H47-N3-O9-S
- MOLECULAR WEIGHT :
- 625.86
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Human Cells - not otherwise specified
- DOSE/DURATION :
- 10 nmol/L
- REFERENCE :
- JCINAO Journal of Clinical Investigation. (Rockefeller Univ. Press, 1230 York Ave., New York, NY 10021) V.1- 1924- Volume(issue)/page/year: 76,374,1985
|
Safety Information
| Hazard Codes | F: Flammable;T: Toxic; |
|---|
| Risk Phrases | 11-23/24/25-39/23/24/25 |
|---|
| Safety Phrases | 36/37-45 |
|---|
| RIDADR | UN 1230 3/PG 2 |
|---|
Synonyms
| L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraenyl]-L-cysteinyl-glycine |
| 7,9,11,14-Eicosatetraenoic acid, 6-[[(2R,3Z)-2-[[(1E,4S)-4-amino-4-carboxy-1-hydroxybutylidene]amino]-3-[(carboxymethyl)imino]-3-hydroxypropyl]thio]-5-hydroxy-, (5S,6R,7E,9E,11Z,14Z)- |
| L-γ-Glutamyl-S-[(4S,5R,6E,8E,10Z,13Z)-1-carboxy-4-hydroxy-6,8,10,13-nonadecatetraen-5-yl]-L-cysteinylglycine |
| leukotriene C1 |
| Leukotriene C4 |
| leucotriene C-1 |
| Leukotriene C4 Lipid Maps MS Standard |
| Leucotriene C4 |
| (5S,6R,7E,9E,11Z,14Z)-6-({(2R,3Z)-2-{(E)-[(4S)-4-Amino-4-carboxy-1-hydroxybutylidene]amino}-3-[(carboxymethyl)imino]-3-hydroxypropyl}sulfanyl)-5-hydroxy-7,9,11,14-icosatetraenoic acid |
| LTC4 |
| Glycine, L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinyl- |
| leukotrienec |
| MFCD00151079 |
