Introduction：Basic information about CAS 1015-89-0|Phenanthridin-6(5H)-one, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
6(5H)-Phenanthridinone is a potent PARP-1 inhibitor and immunomodulator. 6(5H)-Phenanthridinone inhibits cell proliferation and can be used in cancer research[1].
Related Catalog
Research Areas >>CancerSignaling Pathways >>Epigenetics >>PARPResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Cell Cycle/DNA Damage >>PARP
References
[1]. Weltin D, et al. Immunosuppressive activities of 6(5H)-phenanthridinone, a new poly(ADP-ribose)polymerase inhibitor. Int J Immunopharmacol. 1995 Apr;17(4):265-71.
Chemical & Physical Properties
Density
1.2±0.1 g/cm3
Boiling Point
274.8±7.0 °C at 760 mmHg
Melting Point
290-292 °C(lit.)
Molecular Formula
C13H9NO
Molecular Weight
195.22
Flash Point
158.7±3.1 °C
Exact Mass
195.068420
PSA
32.86000
LogP
2.81
Vapour Pressure
0.0±0.6 mmHg at 25°C
Index of Refraction
1.642
InChIKey
RZFVLEJOHSLEFR-UHFFFAOYSA-N
SMILES
O=c1[nH]c2ccccc2c2ccccc12
Storage condition
2-8°C
Toxicological Information
CHEMICAL IDENTIFICATION
RTECS NUMBER :
SG0370000
CHEMICAL NAME :
6(5H)-Phenantridinone
CAS REGISTRY NUMBER :
1015-89-0
LAST UPDATED :
199410
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C13-H9-N-O
MOLECULAR WEIGHT :
195.23
WISWESSER LINE NOTATION :
T B666 HMVJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
10 ug/plate
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: LMF-84
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