CAS 1738-25-6|Dimethylaminopropionitrile

Introduction：Basic information about CAS 1738-25-6|Dimethylaminopropionitrile, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles16
7. Synonyms

Common Name	Dimethylaminopropionitrile
CAS Number	1738-25-6	Molecular Weight	98.14630
Density	0.87 g/mL at 25 °C(lit.)	Boiling Point	171 °C750 mm Hg(lit.)
Molecular Formula	C₅H₁₀N₂	Melting Point	−43 °C(lit.)
MSDS	ChineseUSA	Flash Point	145 °F
Symbol	GHS07	Signal Word	Warning

Names

Name	Dimethylaminopropionitrile
Synonym	More Synonyms

Chemical & Physical Properties

Density	0.87 g/mL at 25 °C(lit.)
Boiling Point	171 °C750 mm Hg(lit.)
Melting Point	−43 °C(lit.)
Molecular Formula	C₅H₁₀N₂
Molecular Weight	98.14630
Flash Point	145 °F
Exact Mass	98.08440
PSA	27.03000
LogP	0.46168
Vapour Pressure	1.24mmHg at 25°C
Index of Refraction	n20/D 1.426(lit.)
InChIKey	MTPJEFOSTIKRSS-UHFFFAOYSA-N
SMILES	CN(C)CCC#N
Water Solubility	0.5 g/L (20 ºC)

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UG1575000

CHEMICAL NAME :: Propionitrile, 3-(dimethylamino)-

CAS REGISTRY NUMBER :: 1738-25-6

BEILSTEIN REFERENCE NO. :: 0773779

LAST UPDATED :: 199710

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C5-H10-N2

MOLECULAR WEIGHT :: 98.17

WISWESSER LINE NOTATION :: NC2N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,923,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,923,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2600 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,923,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00201

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1410 uL/kg

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 10 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO DIMETHYLAMINOPROPIONITRILE-air:min expos to NIAX REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3293 No. of Facilities: 145 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 1990 (estimated)

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302 + H312-H319
Precautionary Statements	P280-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn: Harmful;
Risk Phrases	R21;R36/38
Safety Phrases	S26-S36/37-S24/25
RIDADR	2927
WGK Germany	1
RTECS	UG1575000
Packaging Group	II
Hazard Class	6.1(a)
HS Code	29269095

Customs

HS Code	2926909090
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles16

The urotoxic effects of N,N'-dimethylaminopropionitrile. 2. In vivo and in vitro metabolism.

Toxicol. Appl. Pharmacol. 110(1) , 61-9, (1991)

The urotoxicity and metabolism of N,N'-dimethylaminopropionitrile (DMAPN) were investigated in male Sprague-Dawley rats. Animals treated with 525 mg DMAPN/kg or equimolar doses of commercially availab...

Purification of RNA molecules by gel techniques.

Meth. Enzymol. 180 , 14-25, (1989)

[Morbidity study of employees exposed to dimethylaminopropionitrile].

Zentralbl. Arbeitsmed. Arbeitsschutz. Prophyl. Ergonomie 32(5) , 181-4, (1982)

Synonyms

2-DIMETHYLAMINOETHYL CYANIDE

Cyanogum41catalyst

MFCD00001957

3-(Dimethylamino)propanenitrile

3-(DIMETHYLAMINO)PROPIONITRILE

EINECS 217-090-4

Dimethylaminopropion

3-(N,N-dimethylamino)-propionitrile

3-dimethylaminopropannitril

3-(dimethylamino)-propionitril

2-Dimthylaminoethyl cyanide

DMAPN

3-Dimethylaminopropanonitrile

β-Dimethylaminopropionitrile

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