Introduction： Basic information about CAS 6027-98-1|HARMALINE HYDROCHLORIDE DIHYDRATE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name HARMALINE HYDROCHLORIDE DIHYDRATE CAS Number 6027-98-1 Molecular Weight 286.75500 Density / Boiling Point 426.4ºC at 760 mmHg Molecular Formula C13 H19 ClN2 O3 Melting Point 232-240 °C MSDS USA Flash Point 211.7ºC
Names Name harmaline hydrochloride dihydrate Synonym More Synonyms
Chemical & Physical Properties Boiling Point 426.4ºC at 760 mmHg Melting Point 232-240 °C Molecular Formula C13 H19 ClN2 O3 Molecular Weight 286.75500 Flash Point 211.7ºC Exact Mass 286.10800 PSA 55.84000 LogP 2.65060 InChIKey LCEKUHFBUFUSSY-UHFFFAOYSA-N SMILES COc1ccc2c3c([nH]c2c1)C(C)=NCC3.Cl.O.O Storage condition −20°C
Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : MG8750000 CHEMICAL NAME : Harmaline, hydrochloride, dihydrate CAS REGISTRY NUMBER : 6027-98-1 LAST UPDATED : 199106 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C13-H14-N2-O.Cl-H.2H2-O MOLECULAR WEIGHT : 286.79 HEALTH HAZARD DATAACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 120 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea REFERENCE : TRSEAO Transactions of the Royal Society of Edinburgh. (Edinburgh, Scotland) V.1-70, 1783-1979. Volume(issue)/page/year: 47,245,1909 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea REFERENCE : TRSEAO Transactions of the Royal Society of Edinburgh. (Edinburgh, Scotland) V.1-70, 1783-1979. Volume(issue)/page/year: 47,245,1909 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea REFERENCE : TRSEAO Transactions of the Royal Society of Edinburgh. (Edinburgh, Scotland) V.1-70, 1783-1979. Volume(issue)/page/year: 47,245,1909 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TRSEAO Transactions of the Royal Society of Edinburgh. (Edinburgh, Scotland) V.1-70, 1783-1979. Volume(issue)/page/year: 47,245,1909 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Amphibian - frog DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TRSEAO Transactions of the Royal Society of Edinburgh. (Edinburgh, Scotland) V.1-70, 1783-1979. Volume(issue)/page/year: 47,245,1909
Safety Information Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter Hazard Codes Xn,Xi Risk Phrases R36/37/38 Safety Phrases S22-S24/25 RIDADR 1544 WGK Germany 3 RTECS MG8750000 Packaging Group III Hazard Class 6.1(b) HS Code 2933990090
Customs HS Code 2933990090 Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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Apomorphine enhances harmaline-induced tremor in rats.Pharmacol. Rep. 67 , 435-41, (2015)
Harmaline-induced tremor is a well-known model of essential tremor in humans. The aim of the present study was to examine the influence of apomorphine, a non-selective dopamine receptor agonist, on th...
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Synonyms Harmaline hydrochloride EINECS 253-734-0 3,4-DIHYDRO-7-METHOXY-1-METHYL-9H-PYRIDO[3,4-B]-INDOLE HYDROCHLORIDE DIHYDRATE HARMALOL METHYL ETHER HYDROCHLORIDE DIHYDRATE 4,9-dihydro-7-methoxy-1-methyl-3H-Pyrido[3,4-b]indole hydrochloride hydrate HARMALINE HCL DIHYDRATE(RG) MFCD00150052
