CAS 721431-18-1|Biotin-PEG4-acid

Introduction:Basic information about CAS 721431-18-1|Biotin-PEG4-acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBiotin-PEG4-acid
CAS Number721431-18-1Molecular Weight491.59900
Density/Boiling Point/
Molecular FormulaC21H37N3O8SMelting Point/
MSDS/Flash Point/

Names

Name3-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
SynonymMore Synonyms

Biotin-PEG4-acid BiologicalActivity

DescriptionBiotin-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

Molecular FormulaC21H37N3O8S
Molecular Weight491.59900
Exact Mass491.23000
PSA169.75000
LogP1.41800
InChIKeyGYOXFFWLRKVJJX-ZWOKBUDYSA-N
SMILESO=C(O)CCOCCOCCOCCOCCNC(=O)CCCCC1SCC2NC(=O)NC21
Storage condition2-8°C

Synonyms

Biotin-PEG4-Acid
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