CAS 7212-44-4|Nerolidol
Introduction：Basic information about CAS 7212-44-4|Nerolidol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Nerolidol | ||
|---|---|---|---|
| CAS Number | 7212-44-4 | Molecular Weight | 222.366 |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 276.0±0.0 °C at 760 mmHg |
| Molecular Formula | C15H26O | Melting Point | -75 °C |
| MSDS | ChineseUSA | Flash Point | 96.1±0.0 °C |
| Symbol | GHS07, GHS09 | Signal Word | Warning |
Names
| Name | Nerolidol |
|---|---|
| Synonym | More Synonyms |
Nerolidol BiologicalActivity
| Description | Nerolidol is a natural membrane-active sesquiterpene, with antitumor, antibacterial, antifungal and antiparasitic activity[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>ParasiteResearch Areas >>CancerResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>FungalSignaling Pathways >>Anti-infection >>Bacterial |
| References | [1]. Nerolidol, et al. In vitro antileishmanial and cytotoxic activities of nerolidol are associated with changes in plasma membrane dynamics. Biochim Biophys Acta Biomembr. 2019 Jun 1;1861(6):1049-1056. |
Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 276.0±0.0 °C at 760 mmHg |
| Melting Point | -75 °C |
| Molecular Formula | C15H26O |
| Molecular Weight | 222.366 |
| Flash Point | 96.1±0.0 °C |
| Exact Mass | 222.198364 |
| PSA | 20.23000 |
| LogP | 5.32 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.480 |
| Storage condition | 2-8°C |
| Water Solubility | immiscible |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #5116602
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (3),31,1993
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 13,887,1975
Safety Information
| Symbol | GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319-H410 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | JR4977000 |
| HS Code | 29052290 |
Customs
| HS Code | 29052290 |
|---|
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Synonyms
| HuMbertiol |
| 1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl- |
| MFCD00008911 |
| Nerolidol |
| EINECS 230-597-5 |
| 3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol |
| cis/trans-Nerolidol |
| 3,7,11-trimethyldodeca-1,6,10-trien-3-ol |
| FCI-119b |
| trans,cis-nerblidol |
| TRANS-NEROLIDOL |
| NEROLIDOL,TRANS |
