CAS 22006-64-0|ACTH (1-13)

Introduction：Basic information about CAS 22006-64-0|ACTH (1-13), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameACTH (1-13)
CAS Number22006-64-0Molecular Weight1623.83000
Density1.49g/cm3Boiling Point/
Molecular FormulaC75H106N20O19SMelting Point/
MSDS/Flash Point/

Names

Nameacth (1-13)
SynonymMore Synonyms

ACTH (1-13) BiologicalActivity

DescriptionACTH (1-13) is a 13-aa peptide, with cytoprotective effects in the model of ethanol induced gastric lesions in rats.
Related CatalogSignaling Pathways >>Others >>OthersPeptidesResearch Areas >>Inflammation/Immunology
In VitroAdrenocorticotropic hormone (ACTH) is a tropic hormone produced by the anterior pituitary, regulates cortisol and androgen production and is associated with Addison disease, Cushing syndrome and Cushing disease[2].
In VivoACTH (1-13) alone or in combination with met-enkephalin shows potent cytoprotective effects in the model of ethanol induced gastric lesions in rats, and has immunomodulatory effects[1].
References

[1]. Mulabegović N, et al. Pharmacodynamic properties of a combination of met-enkephalin and alpha 1-13 adrenocorticotropic hormone. Med Arh. 2008;62(1):41-4.

[2]. Allen MJ, et al. Adrenocorticotropic Hormone (ACTH). StatPearls. 2018.7.

Chemical & Physical Properties

Density1.49g/cm3
Molecular FormulaC75H106N20O19S
Molecular Weight1623.83000
Exact Mass1622.77000
PSA659.41000
LogP2.71440
Index of Refraction1.684
Storage condition2-8℃

Synonyms

adrenocorticotropic hormone fragment*1-13
aMSH peptide
ADRENOCORTICOTROPIC HORMONE (1-13)
SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL
SYSMEHFRWGKPV
ADRENOCORTICOTROPIC HORMONE (1-13),HUMAN
H-SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-OH
H-SYSMEHFRWGKPV-OH
acth(1-3)
adrenocorticotropic hormone fragment 1-13,human
tridecactide
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