CAS 88283-34-5|11β-HSD1-IN-9

Introduction:Basic information about CAS 88283-34-5|11β-HSD1-IN-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name11β-HSD1-IN-9
CAS Number88283-34-5Molecular Weight266.21900
Density1.32g/cm3Boiling Point363ºC at 760 mmHg
Molecular FormulaC13H9F3N2OMelting Point/
MSDS/Flash Point173.3ºC

Names

Name2-pyrazin-2-yl-1-[4-(trifluoromethyl)phenyl]ethanone

11β-HSD1-IN-9 BiologicalActivity

Description11β-HSD1-IN-9 (compound c4a) is a potent 11β-HSD1 inhibitor with IC50 values of 0.48 and 1.3 µM for human and murine 11β-HSD1, respectively. 11β-HSD1-IN-9 competitively interacts with rat 11β-HSD1. 11β-HSD1-IN-19 can be used in studies of obesity, hyperglycemia and cognitive impairment[1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease

Chemical & Physical Properties

Density1.32g/cm3
Boiling Point363ºC at 760 mmHg
Molecular FormulaC13H9F3N2O
Molecular Weight266.21900
Flash Point173.3ºC
Exact Mass266.06700
PSA42.85000
LogP2.92080
Index of Refraction1.526
InChIKeyUFTKWWYMFSUYDJ-UHFFFAOYSA-N
SMILESO=C(Cc1cnccn1)c1ccc(C(F)(F)F)cc1

Safety Information

Hazard CodesXi: Irritant;
HS Code2933990090

Customs

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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