CAS 102-37-4|Ethyl 3-(3,4-dihydroxyphenyl)acrylate

Introduction：Basic information about CAS 102-37-4|Ethyl 3-(3,4-dihydroxyphenyl)acrylate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameEthyl 3-(3,4-dihydroxyphenyl)acrylate
CAS Number102-37-4Molecular Weight208.211
Density1.3±0.1 g/cm3Boiling Point377.0±32.0 °C at 760 mmHg
Molecular FormulaC11H12O4Melting Point/
MSDS/Flash Point148.4±18.6 °C

Names

NameEthyl 3-(3,4-dihydroxyphenyl)acrylate
SynonymMore Synonyms

Ethyl 3-(3,4-dihydroxyphenyl)acrylate BiologicalActivity

DescriptionEthyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Immunology/Inflammation >>COX
Target

NF-κB

COX-2

In VitroEthyl Caffeate markedly suppresses the lipopolysaccharide (LPS)-induced nitric oxide (NO) production with IC50 of 5.5 μg/ml[1].
References

[1]. Chiang YM, et al. Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin. Br J Pharmacol. 2005 Oct;146(3):352-63.

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point377.0±32.0 °C at 760 mmHg
Molecular FormulaC11H12O4
Molecular Weight208.211
Flash Point148.4±18.6 °C
Exact Mass208.073563
PSA66.76000
LogP1.72
Vapour Pressure0.0±0.9 mmHg at 25°C
Index of Refraction1.612
Storage condition2-8°C

Safety Information

Hazard CodesXi
HS Code2918290000

Customs

HS Code2918290000
SummaryHS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

Synonyms

Ethyl (2E)-3-(3,4-dihydroxyphenyl)acrylate
Ethyl caffeate
MFCD00045754
caffeic acid ethyl ester
(E)-ethyl 3-(3,4-dihydroxyphenyl)acrylate
3,4-Dihydroxycinnamic acid ethyl ester
ethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, ethyl ester
ETHYL TRANS-CAFFEATE
ETHYL 3,4-DIHYDROXYCINNAMATE
2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, ethyl ester, (2E)-
CAS 102286-67-9|FLUORESCEIN MONO-BETA-D-GALACTOPYRANOSIDE
CAS 10374-74-0|7-Tetradecene
Recommended......
CAS 109715-12-0|5-(p-Toluenesu CAS 103626-36-4|9H-Purin-6-ami CAS 1028-40-6|4(1H)-Quinazolin CAS 102185-28-4|4-AMINOPHENYLP CAS 1000340-33-9|3,4-Dibromo-1 CAS 10390-14-4|2β-Hydroxy CAS 104-43-8|4-n-Dodecylphenol CAS 104-40-5|4-Nonylphenol CAS 1035-51-4|3-(4-ETHOXYPHENY CAS 10517-44-9|1,3-Propanediam CAS 10534-86-8|Hexaamminecobal CAS 101646-01-9|3,4-DIFLUORO-5 CAS 1011407-68-3|(R)-3-CHLORO- CAS 1092682-87-5|4-Chloro-3-me CAS 1036260-25-9|3-Aminocyclob CAS 105394-83-0|Decarboxy Cipr CAS 106868-09-1|2,2-DI-N-OCTYL CAS 1005615-47-3|3-(4-BROMO-PY CAS 104775-66-8|2-amino-4-chlo CAS 10569-35-4|2-phenyl-3-(2-t
Disclaimer

This site is a non-commercial website, not accept any sponsorship and advertising. The content is collated from the Internet, does not represent the position of this site, for personal reference only, please distinguish by yourself! The belongs to the original author.

Copyright © 2025 All Rights Reserved.

TOP