CAS 320-77-4|3-carboxy-2,3-dideoxy-1-hydroxypropan-1,2,3-tricarboxylic acid
Introduction：Basic information about CAS 320-77-4|3-carboxy-2,3-dideoxy-1-hydroxypropan-1,2,3-tricarboxylic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3-carboxy-2,3-dideoxy-1-hydroxypropan-1,2,3-tricarboxylic acid | ||
|---|---|---|---|
| CAS Number | 320-77-4 | Molecular Weight | 192.12400 |
| Density | 1.751g/cm3 | Boiling Point | 329.6ºC at 760 mmHg |
| Molecular Formula | C6H8O7 | Melting Point | / |
| MSDS | / | Flash Point | 167.4ºC |
Names
| Name | isocitric acid |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | Isocitric acid is an endogenous metabolite present in Saliva and Cellular_Cytoplasm that can be used for the research of Alzheimer's Disease, Lewy Body Dementia and Anoxia[1][2][3]. |
|---|---|
| Related Catalog | Research Areas >>Neurological Disease |
| Target | Human Endogenous Metabolite |
| In Vitro | Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1]. |
| References | [1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720. [2]. Tsuruoka M, et al. Capillary electrophoresis-mass spectrometry-based metabolome analysis of serum and saliva from neurodegenerative dementia patients. Electrophoresis. 2013 Oct;34(19):2865-72. [3]. Zupke C, et al. Intracellular flux analysis applied to the effect of dissolved oxygen on hybridomas. Appl Microbiol Biotechnol. 1995 Dec;44(1-2):27-36. |
Chemical & Physical Properties
| Density | 1.751g/cm3 |
|---|---|
| Boiling Point | 329.6ºC at 760 mmHg |
| Molecular Formula | C6H8O7 |
| Molecular Weight | 192.12400 |
| Flash Point | 167.4ºC |
| Exact Mass | 192.02700 |
| PSA | 132.13000 |
| Index of Refraction | 1.569 |
| InChIKey | ODBLHEXUDAPZAU-UHFFFAOYSA-N |
| SMILES | O=C(O)CC(C(=O)O)C(O)C(=O)O |
Synonyms
| 1-hydroxypropane-1,2,3-tricarboxylic acid |
| 1-Hydroxy-propan-1,2,3-tricarbonsaeure |
| 1-hydroxy-propane-1,2,3-tricarboxylic acid |
| 3-Methylsaeure-pentanol-(2)-disaeure |
| I-CIT |
| D-isocitrate |
| isocitrate |
| 1-Hydroxytricarballylic acid |
| 1-Hydroxy-1,2,3-propanetricarboxylic acid |
| 3-Carboxy-2,3-dideoxy-1-hydroxypropan-1,2,3-tricarboxylic acid |
