CAS 123-11-5|4-Methoxybenzaldehyde

[1]. Showler AT , et al. Effects of the Botanical Compound p-Anisaldehyde on Horn Fly (Diptera: Muscidae) Repellency, Mortality, and Reproduction. J Med Entomol. 2018 Jan 10;55(1):183-192.

CHEMICAL IDENTIFICATION

RTECS NUMBER :

BZ2625000

CHEMICAL NAME :

p-Anisaldehyde

CAS REGISTRY NUMBER :

123-11-5

LAST UPDATED :

199710

DATA ITEMS CITED :

13

MOLECULAR FORMULA :

C8-H8-O2

MOLECULAR WEIGHT :

136.16

WISWESSER LINE NOTATION :

VHR DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

1510 mg/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity)

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

1859 mg/kg

TOXIC EFFECTS :

Gastrointestinal - necrotic changes Gastrointestinal - other changes Liver - fatty liver degeneration

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

>5 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

1260 mg/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity)

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

55200 ug/kg/30D-I

TOXIC EFFECTS :

Cardiac - changes in heart weight Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in other cell count (unspecified)

MUTATION DATA

TYPE OF TEST :

Mutation in mammalian somatic cells

TEST SYSTEM :

Rodent - mouse Lymphocyte

DOSE/DURATION :

3560 umol/L

REFERENCE :

MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 3,193,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5044 No. of Facilities: 6993 (estimated) No. of Industries: 40 No. of Occupations: 62 No. of Employees: 100333 (estimated) No. of Female Employees: 61328 (estimated)

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