CAS 100-10-7|p-Dimethylaminobenzaldehyde
Introduction：Basic information about CAS 100-10-7|p-Dimethylaminobenzaldehyde, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | p-Dimethylaminobenzaldehyde | ||
|---|---|---|---|
| CAS Number | 100-10-7 | Molecular Weight | 149.190 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 176-177 ºC (17 mmHg) |
| Molecular Formula | C9H11NO | Melting Point | 72-75 °C(lit.) |
| MSDS | USA | Flash Point | 164 ºC |
| Symbol | GHS02, GHS05, GHS07 | Signal Word | Danger |
Names
| Name | 4-Dimethylaminobenzaldehyde |
|---|---|
| Synonym | More Synonyms |
p-Dimethylaminobenzaldehyde BiologicalActivity
| Description | p-Dimethylaminobenzaldehyde (4-Dimethylaminobenzaldehyde) is an organic compound containing amine and aldehyde moieties which is used in Ehrlich's reagent and Kovac's reagent to test for indoles[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Axel Ehmann, et al. The van URK-Salkowski reagent — a sensitive and specific chromogenic reagent for silica gel thin-layer chromatographic detection and identification of indole derivatives. Journal of Chromatography A. Volume 132, Issue 2, 11 February 1977, Pages 267-276. |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 176-177 ºC (17 mmHg) |
| Melting Point | 72-75 °C(lit.) |
| Molecular Formula | C9H11NO |
| Molecular Weight | 149.190 |
| Flash Point | 164 ºC |
| Exact Mass | 149.084061 |
| PSA | 20.31000 |
| LogP | 1.81 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.596 |
| InChIKey | BGNGWHSBYQYVRX-UHFFFAOYSA-N |
| SMILES | CN(C)c1ccc(C=O)cc1 |
| Storage condition | 2-8°C |
| Stability | Stable, but light sensitive. Incompatible with bases, strong oxidizing agents. |
| Water Solubility | 0.3 g/L (20 ºC) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 620 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- HINEL* Hine Laboratories Reports. (San Francisco, CA) Volume(issue)/page/year: AF33(657)-11756,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533441
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533441 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1800 mg/kg/9D-I
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Related to Chronic Data - death
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533441 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80179 No. of Facilities: 622 (estimated) No. of Industries: 8 No. of Occupations: 13 No. of Employees: 6871 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80179 No. of Facilities: 1897 (estimated) No. of Industries: 7 No. of Occupations: 20 No. of Employees: 23642 (estimated) No. of Female Employees: 15264 (estimated)
Safety Information
| Symbol | GHS02, GHS05, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H226-H290-H314-H332-H335 |
| Precautionary Statements | P210-P261-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R22;R52/53 |
| Safety Phrases | S7-S16-S24/25-S26-S61-S45-S39-S36/37/39 |
| RIDADR | UN 2920 8/PG 2 |
| WGK Germany | 1 |
| RTECS | CU5775000 |
| Packaging Group | I; II; III |
| Hazard Class | 6.1 |
| HS Code | 2912210000 |
Customs
| HS Code | 2922399090 |
|---|---|
| Summary | 2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
Articles69
More Articles| In vitro characterization of self-assembled anterior cruciate ligament cell spheroids for ligament tissue engineering. Histochem. Cell Biol. 143(3) , 289-300, (2015) Tissue engineering of an anterior cruciate ligament (ACL) implant with functional enthesis requires site-directed seeding of different cell types on the same scaffold. Therefore, we studied the suitab... | |
| Modulating notochordal differentiation of human induced pluripotent stem cells using natural nucleus pulposus tissue matrix. PLoS ONE 9(7) , e100885, (2014) Human induced pluripotent stem cells (hiPSCs) can differentiate into notochordal cell (NC)-like cells when cultured in the presence of natural porcine nucleus pulposus (NP) tissue matrix. The method p... | |
| Reduced supply of monocyte-derived macrophages leads to a transition from nodular to diffuse lesions and tissue cell activation in silica-induced pulmonary fibrosis in mice. Am. J. Pathol. 185 , 2923-38, (2015) Pulmonary fibrosis (PF) is an intractable disorder with a poor prognosis. Lung macrophages have been reported to regulate both progression and remission of bleomycin-induced diffuse PF. However, it re... |
Synonyms
| N,N-Dimethyl-p-aminobenzaldehyde |
| p-(N,N-Dimethylamino)benzaldehyde |
| p-N,N-Dimethylaminobenzaldehyde |
| Ehrlichs |
| p-dimethylaminobenzaldehyde |
| EINECS 202-819-0 |
| EHRICH'S REAGENT |
| N,N-Dimethyl-4-aminobenzaldehyde |
| Para-Dimethylaminobenzaldehyde |
| p-Formyldimethylaniline |
| 4-(Dimethylamino)benzaldehyde |
| HYDRAZINE-REAGENT |
| 4-N,N-dimethylaminobenzaldehyde |
| MFCD00003381 |
| p-DAB |
| Benzaldehyde, 4-(dimethylamino)- |
| reagensehrlichovo |
| EHRLICH'S REAGENT |
| ERLICH'S REAGENT |
| VHR DN1&1 |
| p-(Dimethylamino)benzaldehyde |
