CAS 38916-34-6|Somatostatin-14

Introduction：Basic information about CAS 38916-34-6|Somatostatin-14, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Somatostatin-14 BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles49
6. Synonyms

Common Name	Somatostatin-14
CAS Number	38916-34-6	Molecular Weight	1637.878
Density	1.4±0.1 g/cm3	Boiling Point	1970.9±65.0 °C at 760 mmHg
Molecular Formula	C₇₆H₁₀₄N₁₈O₁₉S₂	Melting Point	/
MSDS	ChineseUSA	Flash Point	1145.7±34.3 °C

Names

Name	somatostatin
Synonym	More Synonyms

Somatostatin-14 BiologicalActivity

Description	Cyclic somatostatin is a growth hormone-release inhibiting factor used in the treatment of severe, acute hemorrhages of gastroduodenal ulcers. Sequence: H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bridge: Cys3-Cys14).
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>CancerPeptides

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	1970.9±65.0 °C at 760 mmHg
Molecular Formula	C₇₆H₁₀₄N₁₈O₁₉S₂
Molecular Weight	1637.878
Flash Point	1145.7±34.3 °C
Exact Mass	1636.716675
PSA	663.83000
LogP	-4.25
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.670
InChIKey	NHXLMOGPVYXJNR-ATOGVRKGSA-N
SMILES	CC(N)C(=O)NCC(=O)NC1CSSCC(C(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(Cc2ccccc2)NC(=O)C(C(C)O)NC(=O)C(CCCCN)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2ccccc2)NC(=O)C(CC(N)=O)NC(=O)C(CCCCN)NC1=O
Storage condition	−20°C
Water Solubility	H2O: 1 mg/mL \| Soluble in water(25,00°C 1,00 g/L), Methanol.

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	WF8751700

Articles49

Frequency-dependent, cell type-divergent signaling in the hippocamposeptal projection.

J. Neurosci. 34(35) , 11769-80, (2014)

Hippocampal oscillations are critical for information processing, and are strongly influenced by inputs from the medial septum. Hippocamposeptal neurons provide direct inhibitory feedback from the hip...

Role of somatostatin and somatostatin receptor type 2 in postincisional nociception in rats.

Neuropeptides 49 , 47-54, (2015)

Somatostatin (SST) and the somatostatin receptor type 2 (sstr2) are expressed in the superficial part (Laminae I-III) of the dorsal horn of the spinal cord. Since the neurons in these laminae also rec...

Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration.

BMC Biol. 13 , 70, (2015)

In contrast to mammals, the zebrafish has the remarkable capacity to regenerate its pancreatic beta cells very efficiently. Understanding the mechanisms of regeneration in the zebrafish and the differ...

Synonyms

growth hormone inhibiting hormone

15-28-Somatostatin-28

Modustatina

SS-14

L-Alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10-[(1S)-1-hydroxyethyl]-16-(1-hydroxyethyl)-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide

Somatostatin Acetate

Somatofalk

MFCD00076762

Stilamin

GH-RIF

SRIF-A

somatotropin release inhibiting factor

L-Alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine Cyclic (3®14) Disulfide

SRIF

Somatostatin

Somatostatina

EINECS 256-969-7

Aminopan

L-Alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide

Glycinamide, L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-13,25,28-tris(phenylmethyl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacont-37-yl]-

Glycinamide, L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-4-carboxy-10-[(1S)-1-hydroxyethyl]-16-(1-hydroxyethyl)-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-13,25,28-tris(phenylmethyl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacont-37-yl]-

ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS: AGCKNFFWKTFTSC DISULFIDE BRIDGE CYS3-CYS14

Cyclic somatostatin

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