Introduction:Basic information about CAS 13115-71-4|β-Endorphin (30-31) (bovine, camel, mouse, ovine), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | β-Endorphin (30-31) (bovine, camel, mouse, ovine) |
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| CAS Number | 13115-71-4 | Molecular Weight | 203.196 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 643.1±55.0 °C at 760 mmHg |
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| Molecular Formula | C7H13N3O4 | Melting Point | 194°C |
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| MSDS | / | Flash Point | 342.7±31.5 °C |
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Names
| Name | Glycyl-L-glutamine monohydrate |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Glycyl-glutamine (Glycyl-L-glutamine), as a enzymatic cleavage product of β-endorphin, is apparently an endogenous antagonist of beta-endorphin(1-31) in several systems[1]. Glycyl-glutamine (Glycyl-L-glutamine) is an activate and stable glutamine-containing neuropeptide over glutamine (Gln)[2]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| In Vitro | Glycyl-glutamine (Glycyl-L-glutamine) is an activate and stable glutamine-containing neuropeptide. Glycyl-glutamine (Glycyl-L-glutamine) has an advantage over free glutamine (Gln) as growth factors for cell culture during both autoclaving and storage[2]. |
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| In Vivo | Glycyl-glutamine (Glycyl-L-glutamine) (0.3, 0.6, 1.0 and 10.0 nM) can dose-dependently inhibit beta-End-(1-31)-induced hypotension in pentobarbital-anesthetized rats[1]. |
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| References | [1]. Unal CB1, et al. Beta-endorphin-induced cardiorespiratory depression is inhibited by glycyl-L-glutamine, a dipeptide derived from beta-endorphin processing.J Pharmacol Exp Ther. 1994 Nov;271(2):952-8 [2]. Roth E, et al. Influence of two glutamine-containing dipeptides on growth of mammalian cells.In Vitro Cell Dev Biol. 1988 Jul;24(7):696-8. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 643.1±55.0 °C at 760 mmHg |
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| Melting Point | 194°C |
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| Molecular Formula | C7H13N3O4 |
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| Molecular Weight | 203.196 |
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| Flash Point | 342.7±31.5 °C |
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| Exact Mass | 203.090607 |
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| PSA | 144.74000 |
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| LogP | -2.50 |
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| Vapour Pressure | 0.0±4.1 mmHg at 25°C |
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| Index of Refraction | 1.538 |
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| InChIKey | PNMUAGGSDZXTHX-BYPYZUCNSA-N |
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| SMILES | NCC(=O)NC(CCC(N)=O)C(=O)O |
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| Storage condition | 2-8°C |
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| Water Solubility | 154 g/L (20 ºC) |
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Safety Information
| Hazard Codes | Xi:Irritant; |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S23-S24/25-S37/39-S26 |
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| WGK Germany | - |
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| HS Code | 2924199090 |
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Customs
| HS Code | 2924199090 |
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| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| H-Gly-Gln-OH |
| Gly-l-Gln |
| (2S)-5-amino-2-[(2-aminoacetyl)amino]-5-oxopentanoic acid |
| (S)-2-(2-Aminoacetylamino)-4-carbamoylbutyric acid |
| MFCD00077124 |
| L-Glutamine, glycyl- |
| (2S)-5-Amino-2-[(aminoacetyl)amino]-5-oxopentanoic acid |
| ZV2YVQMV1Z &&L or S Form |
| (S)-5-Amino-2-(2-aminoacetamido)-5-oxopentanoic acid |
| Glycyl-L-glutamine |