CAS 13115-71-4|β-Endorphin (30-31) (bovine, camel, mouse, ovine)

Introduction:Basic information about CAS 13115-71-4|β-Endorphin (30-31) (bovine, camel, mouse, ovine), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Nameβ-Endorphin (30-31) (bovine, camel, mouse, ovine)
CAS Number13115-71-4Molecular Weight203.196
Density1.4±0.1 g/cm3Boiling Point643.1±55.0 °C at 760 mmHg
Molecular FormulaC7H13N3O4Melting Point194°C
MSDS/Flash Point342.7±31.5 °C

Names

NameGlycyl-L-glutamine monohydrate
SynonymMore Synonyms

BiologicalActivity

DescriptionGlycyl-glutamine (Glycyl-L-glutamine), as a enzymatic cleavage product of β-endorphin, is apparently an endogenous antagonist of beta-endorphin(1-31) in several systems[1]. Glycyl-glutamine (Glycyl-L-glutamine) is an activate and stable glutamine-containing neuropeptide over glutamine (Gln)[2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
In VitroGlycyl-glutamine (Glycyl-L-glutamine) is an activate and stable glutamine-containing neuropeptide. Glycyl-glutamine (Glycyl-L-glutamine) has an advantage over free glutamine (Gln)  as growth factors for cell culture during both autoclaving and storage[2].
In VivoGlycyl-glutamine (Glycyl-L-glutamine) (0.3, 0.6, 1.0 and 10.0 nM) can dose-dependently inhibit beta-End-(1-31)-induced hypotension in pentobarbital-anesthetized rats[1].
References

[1]. Unal CB1, et al. Beta-endorphin-induced cardiorespiratory depression is inhibited by glycyl-L-glutamine, a dipeptide derived from beta-endorphin processing.J Pharmacol Exp Ther. 1994 Nov;271(2):952-8

[2]. Roth E, et al. Influence of two glutamine-containing dipeptides on growth of mammalian cells.In Vitro Cell Dev Biol. 1988 Jul;24(7):696-8.

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point643.1±55.0 °C at 760 mmHg
Melting Point194°C
Molecular FormulaC7H13N3O4
Molecular Weight203.196
Flash Point342.7±31.5 °C
Exact Mass203.090607
PSA144.74000
LogP-2.50
Vapour Pressure0.0±4.1 mmHg at 25°C
Index of Refraction1.538
InChIKeyPNMUAGGSDZXTHX-BYPYZUCNSA-N
SMILESNCC(=O)NC(CCC(N)=O)C(=O)O
Storage condition2-8°C
Water Solubility154 g/L (20 ºC)

Safety Information

Hazard CodesXi:Irritant;
Risk PhrasesR36/37/38
Safety PhrasesS23-S24/25-S37/39-S26
WGK Germany-
HS Code2924199090

Customs

HS Code2924199090
Summary2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

H-Gly-Gln-OH
Gly-l-Gln
(2S)-5-amino-2-[(2-aminoacetyl)amino]-5-oxopentanoic acid
(S)-2-(2-Aminoacetylamino)-4-carbamoylbutyric acid
MFCD00077124
L-Glutamine, glycyl-
(2S)-5-Amino-2-[(aminoacetyl)amino]-5-oxopentanoic acid
ZV2YVQMV1Z &&L or S Form
(S)-5-Amino-2-(2-aminoacetamido)-5-oxopentanoic acid
Glycyl-L-glutamine
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