CAS 88404-25-5|4-(Bromomethyl)-6,7-dimethoxy-2H-chromen-2-one
| Common Name | 4-(Bromomethyl)-6,7-dimethoxy-2H-chromen-2-one | ||
|---|---|---|---|
| CAS Number | 88404-25-5 | Molecular Weight | 299.117 |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 417.1±45.0 °C at 760 mmHg |
| Molecular Formula | C12H11BrO4 | Melting Point | 212-216 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 206.0±28.7 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 4-Bromomethyl-6,7-dimethoxycoumarin |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | 4-Bromomethyl-6,7-dimethoxycoumarin is a fluorescent label for carboxylic acids in chromatographic detection[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
| References | [1]. Amet Y, et, al. Simultaneous radiometric and fluorimetric detection of lauric acid metabolites using high-performance liquid chromatography following esterification with 4-bromomethyl-6,7-dimethoxycoumarin in human and rat liver microsomes. J Chromatogr B Biomed Appl. 1996 Jun 7;681(2):233-9. [2]. R.Farinotti, et al. 4-Bromomethyl-6,7-dimethoxycoumarin as a fluorescent label for carboxylic acids in chromatographic detection. Journal of Chromatography A.Volume 269, 1983, Pages 81-90. |
Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 417.1±45.0 °C at 760 mmHg |
| Melting Point | 212-216 °C(lit.) |
| Molecular Formula | C12H11BrO4 |
| Molecular Weight | 299.117 |
| Flash Point | 206.0±28.7 °C |
| Exact Mass | 297.984070 |
| PSA | 48.67000 |
| LogP | 2.70 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.579 |
| InChIKey | JGODLBJJCNQFII-UHFFFAOYSA-N |
| SMILES | COc1cc2oc(=O)cc(CBr)c2cc1OC |
| Storage condition | Refrigerator |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful;C: Corrosive; |
| Risk Phrases | R22 |
| Safety Phrases | S26 |
| RIDADR | 1759 |
| WGK Germany | 3 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 2932209090 |
Customs
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles19
More Articles| Simultaneous radiometric and fluorimetric detection of lauric acid metabolites using high-performance liquid chromatography following esterification with 4-bromomethyl-6,7-dimethoxycoumarin in human and rat liver microsomes. J. Chromatogr. B, Biomed. Appl. 681(2) , 233-9, (1996) The formation of (omega-1)-hydroxylauric acid from lauric acid (LA) can be used as an indicator of the activity of cytochrome P450 2E1 (CYP2E1) in rat and human liver microsomes. A high-performance li... | |
| Labeling of immunoglobulins with bifunctional, sulfhydryl-selective, and photoreactive coumarins. Bioconjug. Chem. 4(4) , 300-4, (1993) 4-(Bromomethyl)-6,7-dimethoxy-2-oxo-2H-benzopyran (1a) and 4-(bromomethyl)-7-methoxy-2-oxo-2H-benzopyran (1b) and their iodo analogs (2) reacted selectively with the sulfhydryl groups generated in a l... | |
| Investigation of derivatization reagents for the analysis of diarrhetic shellfish poisoning toxins by liquid chromatography with fluorescence detection. Nat. Toxins 2(5) , 302-11, (1994) Several derivatization reagents for the conversion of okadaic acid and related DSP toxins to fluorescent derivatives for analysis by liquid chromatography have been examined, viz: 9-anthryldiazomethan... |
Synonyms
| 2H-1-Benzopyran-2-one, 4-(bromomethyl)-6,7-dimethoxy- |
| 4-(Bromomethyl)-6,7-dimethoxy-2H-chromen-2-one |
| 4-(Bromomethyl)-6,7-dimethoxy-2-oxo-2H-benzopyran |
| MFCD00011570 |
| 4-(bromomethyl)-6,7-dimethoxychromen-2-one |
