CAS 122946-43-4|Telmesteine

Introduction：Basic information about CAS 122946-43-4|Telmesteine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Telmesteine BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	Telmesteine
CAS Number	122946-43-4	Molecular Weight	205.23
Density	1.409g/cm3	Boiling Point	386.221ºC at 760 mmHg
Molecular Formula	C₇H₁₁NO₄S	Melting Point	98ºC
MSDS	/	Flash Point	187.38ºC

Names

Name	(4R)-3-ethoxycarbonyl-1,3-thiazolidine-4-carboxylic acid
Synonym	More Synonyms

Telmesteine BiologicalActivity

Description	Telmesteine is an amucolitic agent. Telmesteine has anti-protease activity. Telmesteine inhibits LPS-induced NO production in RAW264.7 cells. Telmesteine can be used for research of inflammation, such as acute and chronic bronchitis and obstructive airways disease[1][2].
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References	[1]. Lee J, et al. Absorption, distribution, metabolism and excretion of telmesteine, a mucolitic agent, in rat. Xenobiotica. 2003 Jul;33(7):755-65. [2]. Xuetao Xu, et al. Evaluation of the anti-inflammatory properties of telmesteine on inflammation-associated skin diseases. RSC Adv., 2017, 7, 34699-34704.

Description

Telmesteine is an amucolitic agent. Telmesteine has anti-protease activity. Telmesteine inhibits LPS-induced NO production in RAW264.7 cells. Telmesteine can be used for research of inflammation, such as acute and chronic bronchitis and obstructive airways disease[1][2].

Related Catalog

Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology

References

[1]. Lee J, et al. Absorption, distribution, metabolism and excretion of telmesteine, a mucolitic agent, in rat. Xenobiotica. 2003 Jul;33(7):755-65.

[2]. Xuetao Xu, et al. Evaluation of the anti-inflammatory properties of telmesteine on inflammation-associated skin diseases. RSC Adv., 2017, 7, 34699-34704.

Chemical & Physical Properties

Density	1.409g/cm3
Boiling Point	386.221ºC at 760 mmHg
Melting Point	98ºC
Molecular Formula	C₇H₁₁NO₄S
Molecular Weight	205.23
Flash Point	187.38ºC
Exact Mass	205.04100
PSA	92.14000
LogP	0.54030
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.562
InChIKey	XBJWOGLKABXFJE-YFKPBYRVSA-N
SMILES	CCOC(=O)N1CSCC1C(=O)O

Safety Information

HS Code	2934999090

Customs

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

(R)-3-(Ethoxycarbonyl)thiazolidine-4-carboxylic acid

Telmesteinum

Telmesteine (INN)

Telmesteine

Telmesteina

(R)-thiazolidine-3,4-dicarboxylic acid-3-ethyl ester

Reolase (TN)

N-ethoxycarbonyl-D-thiazolidine-4-carboxylic acid

(R)-Thiazolidin-3,4-dicarbonsaeure-3-aethylester

Telmesteinum [INN-Latin]

UNII-124I3FE35T

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