Introduction：Basic information about CAS 54110-25-7|Pirozadil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Pirozadil |
|---|
| CAS Number | 54110-25-7 | Molecular Weight | 527.52000 |
|---|
| Density | 1.244g/cm3 | Boiling Point | 594ºC at 760mmHg |
|---|
| Molecular Formula | C27H29NO10 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 313ºC |
|---|
Names
| Name | [6-[(3,4,5-trimethoxybenzoyl)oxymethyl]pyridin-2-yl]methyl 3,4,5-trimethoxybenzoate |
|---|
| Synonym | More Synonyms |
|---|
Pirozadil BiologicalActivity
| Description | Pirozadil is a hypolipidemic agent. |
|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
|---|
| In Vivo | Pirozadil is a hypolipidemic agent. Pirozadil's effect on increasing cerebral blood flow is almost equal to that of papaverine, less than that of nicardipine and much greater than that of the other hypolipidemic/antiatherogenic drugs, nicotinic acid and pyridinol carbamate. Pirozadil is also shown to significantly diminish vascular cerebral resistance to a much greater degree than nicotinic acid and pyridinol carbamate[1]. |
|---|
| References | [1]. Roca J, et al. Effect of pirozadil on cerebral blood flow in anesthetized dogs. Methods Find Exp Clin Pharmacol. 1981 Nov-Dec;3(6):397-401. |
|---|
Chemical & Physical Properties
| Density | 1.244g/cm3 |
|---|
| Boiling Point | 594ºC at 760mmHg |
|---|
| Molecular Formula | C27H29NO10 |
|---|
| Molecular Weight | 527.52000 |
|---|
| Flash Point | 313ºC |
|---|
| Exact Mass | 527.17900 |
|---|
| PSA | 120.87000 |
|---|
| LogP | 3.84720 |
|---|
| Index of Refraction | 1.559 |
|---|
| InChIKey | DIIBXMIIOQXTHW-UHFFFAOYSA-N |
|---|
| SMILES | COc1cc(C(=O)OCc2cccc(COC(=O)c3cc(OC)c(OC)c(OC)c3)n2)cc(OC)c1OC |
|---|
| Storage condition | 2-8℃ |
|---|
Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DI0878200
- CHEMICAL NAME :
- Benzoic acid, 3,4,5-trimethoxy-, 2,6-pyridinediylbis(methylene) ester
- CAS REGISTRY NUMBER :
- 54110-25-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C27-H29-N-O10
- MOLECULAR WEIGHT :
- 527.57
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AFTOD7 Archivos de Farmacologia y Toxicologia. (Universidad Complutense, Facultad de Medicina, Departamento Coordinado de Farmacologia, Ciudad Universitaria, Madrid 3, Spain) V.1- 1975- Volume(issue)/page/year: 6,41,1980
|
Safety Information
Customs
| HS Code | 2933399090 |
|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|---|
Synonyms
| 2,6-Pyridinediyldimethylene bis(3,4,5-trimethoxybenzoate) |
| 2,6-Pyridinediylbis(methylene) 3,4,5-trimethoxybenzoate |
| Benzoic acid,3,4,5-trimethoxy-,2,6-pyridinediylbis(methylene) ester |
| EINECS 258-978-1 |
| Pirozadil |
| 722 d |
| Pirozadilum [INN-Latin] |
| Pemix |
| 2,6-Pyridinedimethanol bis(3,4,5-trimethoxybenzoate) |
