Introduction：Basic information about CAS 22619-35-8|Tioclomarol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tioclomarol |
|---|
| CAS Number | 22619-35-8 | Molecular Weight | 447.33 |
|---|
| Density | 1.519g/cm3 | Boiling Point | 618.9ºC at 760mmHg |
|---|
| Molecular Formula | C22H16Cl2O4S | Melting Point | / |
|---|
| MSDS | / | Flash Point | 328.1ºC |
|---|
Names
| Name | 3-[3-(4-chlorophenyl)-1-(5-chlorothiophen-2-yl)-3-hydroxypropyl]-4-hydroxychromen-2-one |
|---|
| Synonym | More Synonyms |
|---|
Tioclomarol BiologicalActivity
| Description | Tioclomarol, a coumarin anticoagulant, is a vitamin K antagonist[1]. |
|---|
| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others |
|---|
| References | [1]. Isabelle Fourel, et al. Validation of a new liquid chromatography- tandem mass spectrometry ion-trap technique for the simultaneous determination of thirteen anticoagulant rodenticides, drugs, or natural products. J Anal Toxicol. 2010 Mar;34(2):95-102. [2]. Pengo V. Management of oral anticoagulant treatment in patients with venous thromboembolism. Semin Thromb Hemost. 2006;32(8):781-786. |
|---|
Chemical & Physical Properties
| Density | 1.519g/cm3 |
|---|
| Boiling Point | 618.9ºC at 760mmHg |
|---|
| Molecular Formula | C22H16Cl2O4S |
|---|
| Molecular Weight | 447.33 |
|---|
| Flash Point | 328.1ºC |
|---|
| Exact Mass | 446.01500 |
|---|
| PSA | 98.91000 |
|---|
| LogP | 6.12250 |
|---|
| Vapour Pressure | 3.55E-16mmHg at 25°C |
|---|
| Index of Refraction | 1.701 |
|---|
| InChIKey | WRGOVNKNTPWHLZ-UHFFFAOYSA-N |
|---|
| SMILES | O=c1oc2ccccc2c(O)c1C(CC(O)c1ccc(Cl)cc1)c1ccc(Cl)s1 |
|---|
Synonyms
| 3-[3-(4-chlorophenyl)-1-(5-chlorothiophen-2-yl)-3-hydroxypropyl]-2-hydroxy-4h-chromen-4-one |
| tioclomarol |
| Tioclomarolum [INN-Latin] |
| Tioclomarolum |
| UNII-E5B7C16LFK |
| Apegmone |
| Tioclomarol (INN) |
