CAS 7432-23-7|H-Glu(Tyr-OH)-OH

Introduction:Basic information about CAS 7432-23-7|H-Glu(Tyr-OH)-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameH-Glu(Tyr-OH)-OH
CAS Number7432-23-7Molecular Weight310.30
Density1.414g/cm3Boiling Point690.4ºC at 760 mmHg
Molecular FormulaC14H18N2O6Melting Point/
MSDS/Flash Point371.3ºC

Names

NameH-gamma-Glu-Tyr-OH
SynonymMore Synonyms

H-Glu(Tyr-OH)-OH BiologicalActivity

Descriptionγ-Glu-Tyr, a competitive inhibitor of dipeptidyl peptidase-IV (DPP-IV) (IC50=6.77 mM), is a potentially functional component of the type 2 diabetes diet[1].
Related CatalogSignaling Pathways >>Metabolic Enzyme/Protease >>Dipeptidyl PeptidaseResearch Areas >>Metabolic Disease
Target

DPP-4:6.77 mM (IC50)

References

[1]. Yang J, et al. γ‐Glu‐Met synthesised using a bacterial glutaminase as a potential inhibitor of dipeptidyl peptidase IV[J]. International Journal of Food Science & Technology, 2018, 53(5): 1166-1175.

Chemical & Physical Properties

Density1.414g/cm3
Boiling Point690.4ºC at 760 mmHg
Molecular FormulaC14H18N2O6
Molecular Weight310.30
Flash Point371.3ºC
Exact Mass310.11600
PSA149.95000
LogP0.78740
Index of Refraction1.606
InChIKeyVVLXCWVSSLFQDS-QWRGUYRKSA-N
SMILESNC(CCC(=O)NC(Cc1ccc(O)cc1)C(=O)O)C(=O)O

Synonyms

g-L-Glutamyl-L-tyrosine
H-GLU(TYR-OH)-OH
2-amino-5-[[1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-5-oxopentanoic acid
H-Glu-Tyr-OH
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