CAS 70195-20-9|H-Gly-Gly-Tyr-Arg-OH
| Common Name | H-Gly-Gly-Tyr-Arg-OH | ||
|---|---|---|---|
| CAS Number | 70195-20-9 | Molecular Weight | 451.48 |
| Density | 1.49g/cm3 | Boiling Point | / |
| Molecular Formula | C19H29N7O6 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
Names
| Name | gly-gly-tyr-arg |
|---|---|
| Synonym | More Synonyms |
H-Gly-Gly-Tyr-Arg-OH BiologicalActivity
| Description | Papain inhibitor (Glycylglycyl-L-tyrosyl-L-arginine) acts as an effective competitive inhibitor to papain, with a Ki of 9 μM at pH 6.2[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Metabolic Enzyme/Protease >>Cathepsin |
| Target | Papain[1]. |
| References | [1]. Plumb K, et al. Interaction of a ferrocenoyl-modified peptide with papain: toward protein-sensitive electrochemical probes. Bioconjug Chem. 2003 May-Jun;14(3):601-6. |
Chemical & Physical Properties
| Density | 1.49g/cm3 |
|---|---|
| Molecular Formula | C19H29N7O6 |
| Molecular Weight | 451.48 |
| Exact Mass | 451.21800 |
| PSA | 232.75000 |
| LogP | 0.39100 |
| Index of Refraction | 1.652 |
| InChIKey | FJPHHBGPPJXISY-KBPBESRZSA-N |
| SMILES | NCC(=O)NCC(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCN=C(N)N)C(=O)O |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
Articles9
More Articles| A novel method for the incorporation of glycoprotein-derived oligosaccharides into neoglycopeptides. Bioconjug. Chem. 3(5) , 391-6, (1992) We describe a new method for the transfer of carbohydrate moieties to polypeptides in which complex carbohydrate, in the form of glycosyl amino acid, is removed from an available glycoprotein, derivat... | |
| High-resolution separation of peptides by sodium dodecyl sulfate-polyacrylamide gel "focusing". Electrophoresis 29 , 1749-52, (2008) As a follow-up of our previous report (Anal. Chem. 2007, 79, 821-827) on analytical SDS-PAGE focusing, a refinement of the method for separation of peptides in the small to medium M(r) range (0.5-10 k... | |
| Affinity chromatographic purification of papain. Int. J. Pept. Protein Res. 13 , 296, (1979) The reinvestigation of the affinity chromatographic method of purifying papain has been carried out. It has been reported that papain could be purified by taking advantage of the affinity of the enzym... |
Synonyms
| GLYCINE-GLYCINE-TYROSINE-ARGININE |
| PAPAIN INHIBITOR |
| glycyl-glycyl-tyrosyl-arginine |
| H-Gly-Gly-Tyr-Arg-OH |
