CAS 14216-03-6|Hederacoside C
| Common Name | Hederacoside C | ||
|---|---|---|---|
| CAS Number | 14216-03-6 | Molecular Weight | 1221.378 |
| Density | 1.5±0.1 g/cm3 | Boiling Point | / |
| Molecular Formula | C59H96O26 | Melting Point | 222ºC (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | kalopanaxsaponin B |
|---|---|
| Synonym | More Synonyms |
Hederacoside C BiologicalActivity
| Description | Hederacoside C is a principal bioactive pharmaceutical ingredient of Hedera helix leaf that can treat respiratory disorders, because of its expectorant, bronchodilator, antibacterial, and bronchospasmolytic effects. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>InfectionNatural Products >>Terpenoids and Glycosides |
| References | [1]. Rehman SU et al. An ultra-high-performance liquid chromatography-tandem mass spectrometric method for the determination ofhederacoside C, a drug candidate for respiratory disorder, in rat plasma. J Pharm Biomed Anal. 2016 Jun 24;129:90-95. [2]. Kim JM et al. Pharmacokinetics of hederacoside C, an active ingredient in AG NPP709, in rats. Xenobiotica. 2013 Nov;43(11):985-92. |
Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Melting Point | 222ºC (dec.)(lit.) |
| Molecular Formula | C59H96O26 |
| Molecular Weight | 1221.378 |
| Exact Mass | 1220.619019 |
| PSA | 412.82000 |
| LogP | 4.52 |
| Index of Refraction | 1.637 |
| InChIKey | RYHDIBJJJRNDSX-MCGLQMIESA-N |
| SMILES | CC1OC(OC2C(CO)OC(OCC3OC(OC(=O)C45CCC(C)(C)CC4C4=CCC6C7(C)CCC(OC8OCC(O)C(O)C8OC8OC(C)C(O)C(O)C8O)C(C)(CO)C7CCC6(C)C4(C)CC5)C(O)C(O)C3O)C(O)C2O)C(O)C(O)C1O |
| Storage condition | 2-8°C |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R22 |
| Safety Phrases | 22-24/25 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
Articles7
More Articles| [Studies on the saponin constituents of Kalopanax septemlobus (Thunb.) koidz]. Yao Xue Xue Bao 25(1) , 29-34, (1990) Two crystalline components I and II were isolated from the total saponin of Kalopanax septemlobus (Thunb.) koidz. Crystalline II was identified as kalopanax saponin A and I was named as Kalopanax sapo... | |
| Triterpenoidal saponins from the bark of Kalopanax pictum var. typicum. Arch. Pharm. Res. 14(1) , 19-24, (1991) One new triterpenoidal saponin, saponin F(2) has been isolated from the bark of Kalopanax pictum Nakai var. typicum (Araliaceae), together with one known saponin, kizuta saponin K12 (1). On the basis ... | |
| Antinociceptive and anti-rheumatoidal effects of Kalopanax pictus extract and its saponin components in experimental animals. J. Ethnopharmacol. 79(2) , 199-204, (2002) In the present study, we have attempted to elucidate the active components for rheumatoidal arthritis using chloroform (CHCl(3)), ethylacetate (EtOAc) and n-butanol (BuOH) fractions of the methanol ex... |
Synonyms
| Hederacol |
| Akebia saponin pk |
| 6-Deoxy-α-L-mannopyranosyl-(1->4)-β-D-glucopyranosyl-(1->6)-1-O-[(3β)-3-{[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy}-23-hydroxy-28-oxoolean-12-en-28-yl]-β-D-glucop yranose |
| Hederoside H1 |
| Hederacauide D |
| Glycoside L-H2 |
| kizutasaponin K12 |
| Tauroside H2 |
| hederasaponin C |
| Hederacoside C |
| β-D-Glucopyranose, O-6-deoxy-α-L-mannopyranosyl-(1->4)-O-β-D-glucopyranosyl-(1->6)-1-O-[(3β)-3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxy-28-oxoolean- 12-en-28-yl]- |
| Astrantiasaponin H |
