CAS 104992-55-4|Bz-rA Phosphoramidite

Introduction：Basic information about CAS 104992-55-4|Bz-rA Phosphoramidite, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBz-rA Phosphoramidite
CAS Number104992-55-4Molecular Weight988.193
Density/Boiling Point/
Molecular FormulaC53H66N7O8PSiMelting Point/
MSDS/Flash Point/

Names

NameN-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]benzamide
SynonymMore Synonyms

Bz-rA Phosphoramidite BiologicalActivity

DescriptionBz-rA Phosphoramidite is used for ribonucleotides modification[1].
Related CatalogSignaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA SynthesisResearch Areas >>Others
References

[1]. Elise Malek-Adamian, et al. 4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing. J Am Chem Soc. 2017 Oct 18;139(41):14542-14555.

Chemical & Physical Properties

Molecular FormulaC53H66N7O8PSi
Molecular Weight988.193
Exact Mass987.447998
PSA177.93000
LogP13.07
InChIKeyFFXHNCNNHASXCT-RFMFGJHUSA-N
SMILESCOc1ccc(C(OCC2OC(n3cnc4c(NC(=O)c5ccccc5)ncnc43)C(O[Si](C)(C)C(C)(C)C)C2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard CodesXi
RIDADRNONH for all modes of transport

Synonyms

Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-
Bz-rA Phosphoramidite
Bz-rAPhosphoramidite
N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)adenosine 3'-O-(2-cyanoethyl N,N-diisopropylphosphoramidite)
N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine
N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
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