CAS 88546-55-8|Omeprazole Sulfone
| Common Name | Omeprazole Sulfone | ||
|---|---|---|---|
| CAS Number | 88546-55-8 | Molecular Weight | 361.415 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 599.3±60.0 °C at 760 mmHg |
| Molecular Formula | C17H19N3O4S | Melting Point | 80-82ºC |
| MSDS | ChineseUSA | Flash Point | 316.2±32.9 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfonyl]-1H-benzimidazole |
|---|---|
| Synonym | More Synonyms |
Omeprazole Sulfone BiologicalActivity
| Description | Omeprazole sulfone is a metabolite of Omeprazole, which is a proton pump inhibitor. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Others |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 599.3±60.0 °C at 760 mmHg |
| Melting Point | 80-82ºC |
| Molecular Formula | C17H19N3O4S |
| Molecular Weight | 361.415 |
| Flash Point | 316.2±32.9 °C |
| Exact Mass | 361.109619 |
| PSA | 102.55000 |
| LogP | 3.87 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.609 |
| InChIKey | IXEQEYRTSRFZEO-UHFFFAOYSA-N |
| SMILES | COc1ccc2nc(S(=O)(=O)Cc3ncc(C)c(OC)c3C)[nH]c2c1 |
| Storage condition | -20°C Freezer |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2933990090 |
Customs
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles26
More Articles| Pharmacokinetics of omeprazole and its metabolites in three phases of menstrual cycle. Eur. J. Drug Metab. Pharmacokinet. 40(1) , 13-22, (2015) Omeprazole (OMP) is effective in the treatment of gastric hyperacidity and is metabolized by CYP2C19 and CYP3A4. These enzymes are modulated by estrogen and progesterone which regulate the menstrual c... | |
| CYP2C19 haplotypes in Koreans as a marker of enzyme activity evaluated with omeprazole. J. Clin. Pharm. Ther. 34(4) , 437-46, (2009) CYP2C19 is clinically important in Korea because of the relatively high incidence of poor metabolizers in the population. To fully understand the genetic mechanism of the CYP2C19 defect in poor metabo... | |
| Metabolism of omeprazole after two oral doses in children 1 to 9 months old. Proc. West. Pharmacol. Soc. 48 , 108-9, (2005) Essential oils from onion (Allium cepa L.), garlic (Allium sativum L.), and their main components, such as propyl thiosulfinate oxide (PTSO) are being intended for active packaging with the purpose of... |
Synonyms
| 1H-Benzimidazole,6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl] |
| Omeprazole sulfone |
| 5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfonyl)-1H-benzo[d]imidazole |
| 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]- |
| Omeprazole sulphone |
| BEN501 |
| 5-Methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfonyl}-1H-benzimidazole |
| 5-Methoxy-2-{[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl}-1H-benzimidazole |
| Esomeprazole Impurity 4 |
| Omeprazole metabolite Omeprazole sulfone |
